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15 Cards in this Set
- Front
- Back
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serious cardiac arrhythmias/torsades de pointes can occur with erythromycin and what?
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cisapride
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what type of drug are omeprazole, lansoprazole?
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proton pump inhibitors
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action of misoprostol?
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PGE1 analog - increases production and secretion of gastric mucous barrier, decreases acid production
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drug that can be used to prevent NSAID-induced peptic ulcers, maintain a PDA, and induce labor
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misoprostol
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action of pirenzepine, propantheline?
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muscarinic antagonists - block M1 receptors on ECL cells (decrease histamine secretion) and M3 receptors on parietal cells (decrease H+ secretion) - used for peptic ulcer
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monoclonal antibody to TNF-alpha
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infliximab
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sulfasalazine?
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combination of sulfapyradine (antibacterial) and mesalamine (antinflammatory) activated by colonic bacteria; Rx for Crohn's and UC
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mechanism of ondansetron?
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5-HT3 antagonist - powerful central-acting antiemetic
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overuse of aluminum hydroxide?
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constipation and hypophosphatemia
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overuse of magnesium hydroxide?
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diarrhea
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overuse of calcium carbonate?
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hypercalcemia, rebound acid increase
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all antacids can cause what metabolic disturbance?
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hypokalemia
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antiemetic that can cause Parkinsonian symptoms?
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metoclopramide
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how does cimetidine impact P-450 system?
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potent inhibitor
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H2 blocker with antiandrogenic effect that can decrease renal excretion of creatinine?
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cimetidine
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