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15 Cards in this Set

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  • Back
serious cardiac arrhythmias/torsades de pointes can occur with erythromycin and what?
cisapride
what type of drug are omeprazole, lansoprazole?
proton pump inhibitors
action of misoprostol?
PGE1 analog - increases production and secretion of gastric mucous barrier, decreases acid production
drug that can be used to prevent NSAID-induced peptic ulcers, maintain a PDA, and induce labor
misoprostol
action of pirenzepine, propantheline?
muscarinic antagonists - block M1 receptors on ECL cells (decrease histamine secretion) and M3 receptors on parietal cells (decrease H+ secretion) - used for peptic ulcer
monoclonal antibody to TNF-alpha
infliximab
sulfasalazine?
combination of sulfapyradine (antibacterial) and mesalamine (antinflammatory) activated by colonic bacteria; Rx for Crohn's and UC
mechanism of ondansetron?
5-HT3 antagonist - powerful central-acting antiemetic
overuse of aluminum hydroxide?
constipation and hypophosphatemia
overuse of magnesium hydroxide?
diarrhea
overuse of calcium carbonate?
hypercalcemia, rebound acid increase
all antacids can cause what metabolic disturbance?
hypokalemia
antiemetic that can cause Parkinsonian symptoms?
metoclopramide
how does cimetidine impact P-450 system?
potent inhibitor
H2 blocker with antiandrogenic effect that can decrease renal excretion of creatinine?
cimetidine