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14 Cards in this Set
- Front
- Back
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Villous atrophy with hyperplastic crypts:
Villous atrophy with atrophic crypts: Villi distorted, hyperplastic crypts: |
celiac/tropical sprue
radiation, chemo adjacent to ulcers |
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2% of people, 2 inches long, 2 feet proximal to ileocecal valve, 2 types of choristomas:
Why are intestinal infarcts red? Some causes of venous infarcts? |
Meckel's diverticulum
dual blood supply, anastomoses Strangulation (adhesions, torsion/volvulus, intussusception) |
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Triathletes can sometimes get what pathology? What happens?
What causes fibrosis and narrowing of the affected bowel? |
mucosal infarction - inner portion of bowel dies, serosa remains intact - GI bleed
chronic ischemia of the gut |
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What produces ulcers with their long axes perpendicular to the axis of the bowel in the Peyer's patches?
What produces granulomas with star-shaped microabscesses? What bacteria primarily attacks macrophages causing erythrophagocytosis? |
TB
C. jejuni Y. enterocolitica Salmonella |
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What disease is characterized by longitudinal fissures with transmural inflammation/damage?
What happens to the serosa? How can you tell between Crohn's and ulcerative colitis? |
Crohn's
becomes gray/fibrous, surrounded by fat sarcoid-like granulomas on mucosal biopsy |
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What is unique about Crohn's lesions?
Where is it most commonly found? What drug is effective at eliminating inflammation from Crohn's? |
skip lesions - sharp borders between lesions
terminal ileum infliximab (TNF-a Ab) |
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Endocrine cancer, look/act non-aggressive, often found after metastatic disease appears:
Characteristic histology? |
Carcinoid tumors
neurosecretory granules, bottom of cells |
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What is implicated in carcinoid syndrome?
Classic symptoms? |
serotinin
wheezing, flushing, redness, fibrosis of R endocardium |
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Malabsorption is a defect in what organ?
Maldigestion is a defect in what organ? What is steatorrhea? What stain is used to detect fat? |
Small Intestine
Pancreas excessive fat in stool OIL RED O! |
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Acrodermatitis enteropathica is produced from a lack in ________.
People with diseases involving the terminal ileum tend to lack ________ and ________. |
Zinc
B12, folic acid |
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Coniditon of idiosyncratic reaction to gliadin - Ab's against reticulin and endomysial transglutaminase:
Pathology? Appearance of villi/crypts? Treatment? |
Celiac sprue
cytotoxic T-cells attack epithelium short/no villi, deep crypts gluten-free diet |
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Infection by tropherhyma whippli bacillus, PAS+ rods inside histiocytes/macrophages
Treatment? |
Whipple's disease
long-term Abx - tetracycline, Bactrim |
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inability to break down lactose, milk products cause diarrhea
Patients lacking chylomicrons, VLDL, LDL, acanthocytes (spiny red cells) in cell membranes: |
disaccharidase deficiency (lactose intolerant)
abetalipoproteinemia |
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Fibrous bands following peritonitis; can snare loops of bowel
telescoping of the bowel onto itself, most common in kids twisting of a loop of bowel around its stalk |
adhesions
intussusception volvulus |
