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24 Cards in this Set

  • Front
  • Back
Section taken from appendix

Section taken from appendix

Normal appendix



*Thin serosa, lymphoid tissue in submucosa, no inflammatory cells in muscularis

Section taken from appendix

Section taken from appendix

Acute Appendicitis



*General architecture maintained, but no clear mucosa visible and ulceration apparent


*Presents w/ RLQ pain w/ rebound tenderness and N/V

Section taken from appendix

Section taken from appendix

Acute Appendicitis



*Many neutrophils and some eosinophils that infiltrate b/w smooth mm cells


*Thinned out muscularis makes appendix prone to rupture


*Dilated BV

Section taken from appendix

Section taken from appendix

Normal Appendix



*Red arrow points to colonic epithelium w/ crypts


*Lymphoid follicles in submucosa

From GB

From GB

Chronic Cholecystitis



*Thickened muscularis due to bile sludge or stone obstruction


*Fibrosis


From GB

From GB

Chronic Cholecystitis



*Hypertrophy of mm leads to trapping of epithelium = "Rokitansky-Aschoff Sinus" (blue)


*May find collections of foamy histeocytes


From Parotid Gland

From Parotid Gland

Pleomorphic Adenoma



* Dark purple = normal serous & mucinous glands, Light purple mass = tumor


*Pseudo-encapsulated = high rate of reoccurance


*predominantly in females in parotid


From Parotid Gland

From Parotid Gland

Pleomorphic Adenoma



*Chrondromyxoid tumor of spindle myoepithelial cells and epithelial ductal cells (pink)


*Benign but can transform to malig.

From SI

From SI

Crohn's Disease



*Transmural inflammation (vs. Ulcerative Colitis which is limited to mucosa)


*Tip has fat necrosis that leads to adhesions and fistulas


*Hyperplasia of muscularis propria

From SI

From SI

Crohn's Disease



*Ill-defined granuloma (top)


*Fissure (deep and narrow) ulcer


*Skip Leisons

From Terminal Illeum

From Terminal Illeum

Ulcerative Collitis



*Inflammation limited to mucosa (musclaris is untouched!) -- may spill over into submucosa


From Terminal Illeum

From Terminal Illeum

Ulcerative Collitis



*Broad ulcer in mucosa only


*Continuous leisions

From Terminal Illeum

From Terminal Illeum

Crypt Abscess in Ulcerative Collitis



*Lymphocytes and Neutro's filing cyrpt


*Crypt dropout and loss of normal architecture

From esophagus

From esophagus

Barret's Esophagus



*Salmon-velvety plaque


*Intestinal Metaplasia w/ goblet cells (left)


*Right shows normal of squamous epithelium


*Increased risk of AdenoCA if dysplasia present

From Colon

From Colon

Adenocarcinoma of Colon



*Hyperchromatic cells forming tubular structures and increased mitotic figures w/ desmoplastic stroma (blue star) that indicates invasive CA

From Colon

From Colon

Adenocarcinoma of Colon



*pale right = submucosa


*Blue star = desmoplastic stroma


*Complex/Cribiform Glands (vs normal glands on right)



From Colon

From Colon

"Dirty Necrosis" in Adenocarcinoma of Colon



*Glandular structure filled w/ dead nuclei


*If you find this type of necrosis in liver, you can deduce that it is a MET from colon

From Colon

From Colon

Pedunculated polyp w/ Tubulovillous Adenoma



*villi architecture w/ tubules underneath


*darker purple due to loss of mucus producing goblet cells


*NO dysplasia in stalk = curative polypectomy!

From Colon

From Colon

Pedunculated polyp w/ Tubulovillous Adenoma



*High grade dysplasia indicated by 'pencil-shaped' nuclei, cribiforming/complex glandular vs. lower left corner = low grade

From tongue

From tongue

Squamous Cell Carcinoma of the Mouth



*Desmoplasia (paler area circled) w/ large islands of keratin-producing cells



*Also see SCC in Anus

From Tongue

From Tongue

Squamous Cell Carcinoma of the Mouth



*Keratin pearls indicating SCC


*Assoc. w/ tobacco (chewing & smoking) & EtOH


*NOTE: HPV-driven tumors that occur in post. mouth have more basaloid cell histo

From Liver

From Liver

Alcoholic Steatohepatitis



*Paler than normal liver due to increased fat infiltration


*Inflammatory cells among hepatocytes (*main way to tell this is due to EtOH vs NASH)

From Liver

From Liver

Alcoholic Steatohepatitis



*Mallory Hyaline Bodies = diagnositic!

Trichrome Stain of Liver

Trichrome Stain of Liver

Alcoholic Steatohepatitis



*Blue = Fibrosis


*'Tram-track' (peri-sinusoidal) fibrosis (vs viral hepatitis that has fibrosis in thick bands)


*Fibrosis centered around central vein (zone 3) in both alcoholic liver and NASH