Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
GI Defense |
Flow of liquid, lysozyme, normal flora- oral cavity Peristalsis and flow- esophagus Low pH- Stomach persistalsis, peyer patches, IgA, mucus- SI normal flora, shedding of epi- Colon |
|
|
Specific Defenses |
Antibodies M Cells- Sample and present to peyers patches Commensural Bacteria- compete for nutrients Glycocalyx- in mucin traps bacteria into binding and then excretes in the feces |
|
|
Infectious Onest |
Anatomic Alterations- blind loops lead to lack of flow and foothold establishment Stomach Acid- use of antacids can increase pH and allow bacterial growth Normal Flora Change- broad antibiotics can wipe commensurate flora out allowing other more harmful bacteria in Specific Agents- can be especially virulent and attack the patient |
|
|
Damage |
Enterotoxins- alter normal function and provoke diarrhea and systemic response Local Inflammation- inflitration of the area by bacteria Deep Tissue Invasion- leads to bacteremia Perforation- rupture of lining and peritonitis |
|
|
Mouth Infections |
Often introduced via Fecal-Oral Route Nonpathogenic Flora- combat the ability of new more harmful pathogens Mechanical actions of Tongue and Saliva Antimicrobial Parts of Saliva- Lysozyme and IgA selectively combat recognized antigens. |
|
|
Candidiasis |
Candida Albicans- yeast found in the environment forms pseudo membranes within the oral cavity that can be easily peeled off. Typically in immunocompromised and young children. Treat with Anti-fungal agens like nystatin |
|
|
Stomach Infections |
Typically acid-resistant Gram + organisms: Lactobacillus, Peptostreptococci, Staph, and Strep H. Pylori- assctd. with gastritis and peptic ulcers- produces urease which increases surrounding pH by turning acid into ammonia. Also has flagella |
|
|
H. Pylori |
Gram - helical shaped Infects 1/2 global population, thrives in acid via urease neutralization. Colonizes mucus layer and epithelial surface via VacA toxin (stops T cell) Causes a persistant chronic gastritis---> PUD, cancer, and MALT |
