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25 Cards in this Set
- Front
- Back
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when will a pt have a deficiency of pancreatic amylase?
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CF
chronic pancreatitis pancreatic tumor |
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what does virus diarhea look like?
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watery bc they effect sb
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what can cause acidic stools
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lactose intolerance; anything with undigested carbs bc bacteria ferment carbs into FA, H2 and CO2
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who presents with lactose intolerance?
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older children and adults
asians and africans |
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what is the most common congential disacchariedase deficinency?
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Sucrease
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pt has diarrhea from birth, fail to thrive, dehydration
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congenital disacch def
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what is the treatment for congen dissach def?
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replacement enzyme drops with meals
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what leads to a secondary disaccharide def?
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villous damage:
viral gastroenteritis celiac disease tropical sprue |
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what can rotavirus do?
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cause flatterning of villi-- loss of lactase (at tip)
can become secondarily lactose intolerant |
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what can cause insufficiency of pancreatic enzymes?
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CF
Resection (Whipples) Chronic panceatitis |
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what can cause the duodenum to be acidic and therefore inactivate pancreatic enzymes?
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gastrectomy- removal of pylorus with tumor
vagotomy ZE |
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what condition results in the inability to form chylormicrons?
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abetalipoproteinemia bc the MTTP gene is missing
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What are some fininding in abetalipopro.....?
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presents in early infancy
low or absent VLDL and chylomircron levels fatty, greasy duodenum acanthocytes: scalloped RBCs Fat in enterocytes |
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what does retroperitoneal fibrosis cause?
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fat malabsorption bc lacteals are dilated and stagnant bc lymph is backed up bc fibrosis impedes as lacteal system drains down the back
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what is the presentation of primary enterokinase deficincy?
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diarrhea and fail to thrive from birth
hypoprotenemia edema better over time |
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what does enterokinase do?
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catalyzed trypsinogen to trypsin conversion
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what are the symptoms of celiac disease?
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increasesd intestinal perm
inflamatory response that leads to villious damage autoimmune |
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how can you screen for celiac disease?
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look for antibodies to tTG
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what is a painful itchy symmetric vessical rash associated with?
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celiac disease (thats dematiti herpetiformis)
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what is the clinical presentation of celiac disease
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skinny malnourished big belly poor growth atrophied vili
dermititis herpetiformis |
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how do you Dx whipple's disease?
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you look for PAS pos particles in a biopsy of duodenum; since the lacteals are dilated and villi are blunted they will stain
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what are some symptoms of whipples?
who gets it? treatmetn? |
wt loss, diarrhea, arthralgia, lymphadenopathy, ab pain, fever
white older/middle age male antibiotics |
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how does giardia lamblia cause steatorrhea?
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this flagellated protozoa colonizes the SI leading to villous blunting by sticking to the lining of the SI
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how is giardia transmitted?
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water
person to person |
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what is a complication of necrotizing enterocollitis?
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if premature infant has mutliple cases, a large portion of the SI must be removed leading to small bowel syndrome (malabsorption)
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