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20 Cards in this Set
- Front
- Back
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What does the brain-gut axis consist of?
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Intrinsic motor activity, modulation by the ANS, sensory fibers from the GIT to spine to brain, and 3 areas in the brain that co-ordinate the processing of GI pain
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What is the triad of pathogenisis of IBS?
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Altered perception, altered motility, and visceral hypersensitivity
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What study gives evidence for visceral hypersensitivity?
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Balloon studies--place balloon in people's colons and ask when they can feel it as painful. IBS patients can't handle the balloon being very big-->their intestines are more sensitive to the stretch
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What do PET scans show about IBS?
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IBS patients show no anterior cingulate cortex activity--Normal patients do show activity there
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TRUE/FALSE: The best way to diagnose IBS is with PCR.
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FALSE--no diagnostic test exists, there are no physiological abnormalities
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How do you diagnose IBS?
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Symptoms must fulfill Rome criteria at the exclusion of other diagnoses
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True/False: You never get weight loss with IBD.
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FALSE--unintended weight loss may occur
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What are some differential diagnoses for IBS?
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IBD, colon cancer(check family history), lactose intolerance, CELIAC disease, infectious diarrhea
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Where do diverticuli usually occur?
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Where the vasa recta penetrate the intestinal wall
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What are the pathophysiologies of diverticular disease?
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Colonic wall structure, amount of dietary fiber, and colonic motility(segmentation, elastase deposition, and collagen cross-linking)
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True/False: Elastin deposition increases with age.
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TRUE--this can lead towards diverticulosis
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How do you get diverticulitis?
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First you have the outpocketing diverticulosis and then they get blocked with poop and get infected
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Why would you have urinary symptoms with diverticulitis?
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Because the sigmoid colon sits on the bladder--a fistula can occur here
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What is the treatment for diverticulitis?
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Bowel rest, antibiotics, and analgesia
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What kinds of perforation are known?
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Peritonitis--like a perforated appendix where there is direct opening into the peritoneal cavity
Abscess formation--more concentrated and walled off by fat around the colon |
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True/False: Fistulae can develop between any two epithelialized surfaces
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TRUE
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What is the most common form of fistula?
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Colovesical(50-60%)
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How does GI hemorrhage occur? Is it related to inflammation or diverticulitis?
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Due to rupture of the vasa recta stretched by the diverticula--it is NOT related to diverticulitis
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Where are most diverticuli found? Where are most bleeding diverticuli found?
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In the sigmoid colon--in the right colon
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Who's the coolest girl ever?
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Shorty :)
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