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11 Cards in this Set

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Gastrin
Cell: G
Effects: Increase histamine and gastrin secretion
Increase somatostatin (negative reg)
Increase differentiation and proliferation of stomach/colon cells
Amidated = all of the above
Glycine extended = no acid production
Cholecystekinin
Cell: I
Effects: Increase pancreatic growth and bicarb/water secretion
Decreases gastric emptying
Increases bile secretion
Secretin
Cell: S
Effects: Increases pancreatic bicarb/water secretion
Increases CCK secretion
Inhibits acid/histamine production
Motilin
Cell: M
Effects: Secreted during the interdigestive phase to stimulate the migrating motor complex
**Receptors stimulated by erythromycin
GIP/GLP-1
Cell: K and L
Effects: Increases insulin secretion
Decreases acid secretion and gastric emptying when stimulated by sugars in the SI
Inhibits glucagon secretion and
PYY
Cell: L
Effects: Secreted into the blood to induce the sensation of satiety; diminished in obese people
Somatostatin
Cell: D
Effects: Decreases gastrin release
Decreases insulin secretion
Ghrelin
Cell: X
Effects: Induces sensation of hunger and contractility by binding the hypothalamic-pituitary axis
Histamine
Cell: ECL
Effects: Induces acid secretion when secreted in vesicular and free forms
Nitric oxide
Effects: Vasodilation and relaxation of smooth muscle
Serotonin
Cell: ECL
Effects: regulation of intestinal fluid transport, peristalsis
Critical for visceral sensation and pain