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29 Cards in this Set

  • Front
  • Back
G cells of antrum
gastrin
I cells of duodenum & jejunum
CCK
S cells of duodenum
secretin
D cells of pancreatic islets/GI mucosA
somatostatin
K cells of duodenum/jejunum
GIP
parasympathetic ganglia in sphincters, gallbladder, small intestine
VIP
small intestine (produce MMC)
motilin
mast cells of gastric mucosa
histamine
vagus that innervates G cells of stomach
GRP (bombesin)
mucosal & SM nerves (opiates)
enkephalins
increase gastric H+, gastric mucosa growth & gastric motility
gastrin
increased pancreatic secretion & gallbladder contraction, decrease gastric emptying
CCK
increased pancreatic bicarb * bile secretion, decrease gastric acid secretion
secretin
inhibits release of all GI hormones
somatostatin
decrease gastric H+ secretion and increases insulin release
VIP
increase smooth muscle relaxation, including LES
NO
produces MMC
motilin
used to treat vipoma & carcinoid tumors
somatostatin
increased in ZES
gastrin
phenylalanine & tryptophan stimulate:
gastrin
increased by fatty acids, amino acids, oral glucose
GIp
increased by acid, decreased by vagal stimulation
somatostatin
increased by acid, fatty acid in lumen of duodenum
secretin
increased by fatty acids and amino acids
CCK
increased by stomach distention, amino acids, peptides, vagal stimulation. decreased by stomach pH <1.5
gastrin
increased by distention and vagal stimulation
decreased by adrenergic input
VIP
action: decreases gastric acid secretion and increases insulin release
GIP
action: increases intestinal water and electrolyte secretion, increases relaxation of intestinal smooth muscle and sphincters
VIP
reason why oral load of glucose is used more rapidly than equiv by IV
GIP