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29 Cards in this Set
- Front
- Back
G cells of antrum
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gastrin
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I cells of duodenum & jejunum
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CCK
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S cells of duodenum
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secretin
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D cells of pancreatic islets/GI mucosA
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somatostatin
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K cells of duodenum/jejunum
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GIP
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parasympathetic ganglia in sphincters, gallbladder, small intestine
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VIP
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small intestine (produce MMC)
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motilin
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mast cells of gastric mucosa
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histamine
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vagus that innervates G cells of stomach
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GRP (bombesin)
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mucosal & SM nerves (opiates)
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enkephalins
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increase gastric H+, gastric mucosa growth & gastric motility
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gastrin
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increased pancreatic secretion & gallbladder contraction, decrease gastric emptying
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CCK
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increased pancreatic bicarb * bile secretion, decrease gastric acid secretion
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secretin
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inhibits release of all GI hormones
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somatostatin
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decrease gastric H+ secretion and increases insulin release
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VIP
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increase smooth muscle relaxation, including LES
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NO
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produces MMC
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motilin
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used to treat vipoma & carcinoid tumors
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somatostatin
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increased in ZES
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gastrin
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phenylalanine & tryptophan stimulate:
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gastrin
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increased by fatty acids, amino acids, oral glucose
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GIp
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increased by acid, decreased by vagal stimulation
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somatostatin
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increased by acid, fatty acid in lumen of duodenum
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secretin
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increased by fatty acids and amino acids
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CCK
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increased by stomach distention, amino acids, peptides, vagal stimulation. decreased by stomach pH <1.5
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gastrin
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increased by distention and vagal stimulation
decreased by adrenergic input |
VIP
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action: decreases gastric acid secretion and increases insulin release
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GIP
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action: increases intestinal water and electrolyte secretion, increases relaxation of intestinal smooth muscle and sphincters
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VIP
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reason why oral load of glucose is used more rapidly than equiv by IV
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GIP
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