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10 Cards in this Set
- Front
- Back
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H. pylori was officially "discovered" by:
How? Habitat? |
Marshall, Warren
Marshall ate a H. pylori cx - exhibited symptoms of gastritis exclusively human gastric mucosa |
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Infections are associated with _______ conditions in childhood.
______% of the developed world is colonized. ___ out of 10 peptic ulcers due to H. pylori infection |
crowded, low socioeconomic status
70-90% 9/10 |
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Morphology of H. pylori?
Converts urease to __________. Pathology? |
G-, microaerophilic, spiral/corkscrew shape, up to 7 flagella
ammonia, CO2 local tissue/mucosal injury, increased gastrin, HCl |
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Antacids:
indications? Which are systemic, which are non-systemic? T/F: Antacids reduce acid secretion and production. |
short-term relief of pain from GERD/reflux/PUD
Sodium = Systemic Calcium, Aluminum, Magnesium = non-systemic False - antacids bind to H+ released |
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Rank antacids from highest ANC to lowest:
Which compounds last the longest? |
Ca, Mg, Na, Al (Aluminum sucks)
Ca, Mg |
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What is magaldrate?
A "pro-fart" surfactant: forms viscous solution (alginate) that floats on GI contents, helping with reflux: |
magnesium + aluminum hydroxide combined
simethicone alginic acid |
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Most common SE of aluminum compounds? (aluminum sucks ass)
SE of Mg compounds? SE of Ca compounds? |
Al - constipation
Mg - diarrhea, hypermagnesemia Ca - constipation, hypercalcemia, hypophosphatemia |
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SE of Na compounds?
Which one is associated with "milk-alkali" syndrome? What should you check before recommending a particular antacid? |
Gas/flatulence, hypernatremia
Na compounds electrolyte status - elevated Mg = NO Mg compounds, etc diarrheal/constipation diseases |
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When should you take antacids? Why?
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1 hr before or 2 hrs after other meds - lots of interactions
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Pt with elevated serum Ca, problems with diarrhea - which antacid?
Pt with chronic constipation, elevated Ca levels: Dialysis pt, which one should should you avoid? |
Na, Al
Mg, Al Al |
