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9 Cards in this Set
- Front
- Back
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Metoclopramide MOA
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Prokinetic agent
D2R blocker, releases ACh from myenteric neurons inc. LES sphincter, contraction of stomach, USE: GERD, DMgastroparesis relaxes pyloric sphincter (NO secretions) |
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Cisapride
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facilitates ACh from myenteric plexus
Greater effect on colon, does NOT block D2Rs SE: torsades, HA, TCpenia |
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7 laxatives
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MgCitrate, NaPhosphate
Lactulose Psyllium Mineral Oil Docusate Bisacodyl |
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MgCitrate, NaPhosphate
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Osmotic, 2-6hours evacuation of GI tract (remove parasites)
Sm and Lg. intestines |
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Lactulose
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Osmotic, COLON
NH3 and water pulled into bowel. PORTAL SYSTEMIC ENCEPHALOPATHY |
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Mineral Oil
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Lubricant for Colon to retard absorption of fecal water
May decrease lipid-soluble vitamins; lipid pnemonitis if inhaled |
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Docusate
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Surfactant for sm. Lg. intestine
mixes fat and water to soften stool for hemorrhoids, prevents constipation weak stimulant |
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Bisacodyl
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stimulates sm. mm. peristalsis in colong
ab cramps, chronic use can deteriorate intestinal function |
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3 anti-diarrheal agents
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Diphenoxylate
Lopramide Bismuth Subsalicylate |
