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13 Cards in this Set
- Front
- Back
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5 Types of pathogenic E. coli?
(HI PAT) Characteristics of E. coli? |
-hemorrhagic, -invasive, -pathogenic, -aggregative, -toxigenic
G- bacilli, fecal-oral |
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Cholera-like toxin, *T*raveler's diarrhea:
adheres to small bowel, common in (Pint-sized) children: Shiga-like toxin, O157:H7, inflammatory colitis: |
ETEC
EPEC EHEC |
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Shiga-like, but no toxin, invades colonic epithelium:
in colonic mucosa, +toxin, prolonged watery diarrhea: Which ones are non-inflammatory? (PAT) InvAsive, inflammatory? |
EIEC
EAEC EPEC, EAEC, ETEC EIEC, EAEC |
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SHIga-like?
Montezuma's Revenge? ETEC affects what cell pathways? What does that cause? |
EHEC, EIEC
EAEC more adenylate-cAMP, cGMP more Cl- release, H2O follows |
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What's unique about EPEC's attachment to the cell? (Princess on a Pedestal)
3 stages: stick to mucosa, biofilm formation, cytotoxin, intestinal cell damage: |
attaching and effacing - EPEC injects tir receptor, binds to intimin, rearranges actin in the cell --> pedestal, bacteria on top
EAEC |
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Has 3 stages: mucosal adherence, *biofilm*, cytotoxin/intestinal cell damage
Why is pathogenic E. coli pink on MacConkey's agar? What E. coli are related to S(HI)gella? |
EAEC
lactose fermenter EHEC, EIEC |
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EHEC usually affects what systems?
Complications? (E-*H*-E-C) Which bacteria do you AVOID ABX use? Why? |
large bowel - necrosis, neutrophils
kidneys - shiga toxin hemorrhagic colitis, HUS EHEC - kills bacteria --> more toxin released |
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Major risk in maternal infection during pregnancy:
affects immunocompromised, long-term abx use, pseudomembranous colitis |
L. monocytogenes
C. diff |
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anaerobic, G+ rod, spore forming, nonsocomial infections:
Why does C. diff cause watery diarrhea? Tx for C. diff? |
C. diff
less normal flora --> less carb digestion --> osmotic H2O into intestine IVF, stop Abx if possible, replace normal flora |
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Review:
Three most common causes of acute infectious diarrhea: causes typhoid fever: |
Shigella, Salmonella, Campylobacter
Salmonella typhi |
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Which bacteria cause large volume, watery diarrhea? Why?
mucoid/bloody diarrhea - which bacteria? Why? |
ETEC, C. perfringens, Vibrio, B. cereus, S. aureus - toxins --> more water in feces
EHEC, Shigella, Salmonella, Campylobacter, Yersinia - more invasive, leukocytes in feces, immune response |
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Traveled recently?
seafood lately? systemic Abx? mayonnaise, cream puffs? |
campylobacter, E. histolytica, ETEC, salmonella, shigella, cryptosporidium
Vibrio C. diff S. aureus |
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Rice, starchy foods?
major S/S of invasive GE? Just need toxin, not necessarily bacteria: |
B. cereus
leukocytes and blood in stool, fever S. aureus, B. cereus, C. perfringens, botulinum |
