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50 Cards in this Set

  • Front
  • Back

Causes of Peptic Ulcer Disease

H.pylori >90% duodenal ulcers >75% gastric



Meds such as NSAIDS, ASA, glucocorticoids


more common in men


more common in >1/2 PPD smokers


Type A personalities?



Duodenal ulcers: 30-35


Gastric ulcers: 55-65

S/S Peptic ulcers

gnawing epigastric pain


relief with eating (duodenal)


pain worse with eating (gastric)

PE Peptic ulcers

may have some mild epigastric tenderness


GI bleeding


Perforation (board like abdomen)


quiet bowel sounds


ridgidity

Lab/Dignostics Peptic Ulcers

may have some anemia on CBC


consider endoscopy after 8-12 weeks treatment


consider H.pylori testing

Management of Peptic ulcers

H2 Receptor Antagonists



Proton Pump Inhibitors

H2 Receptor Antagonists

Tagament (Cimetidine)


Ranitidine (Zantac)


Famotidine (Pepcid)


Nizatindine (Axid)



"INES"

Proton Pump Inhibitors

Take 30 minutes before meals



"ZOLES"



Lansoprazole (prevacid)


Rabeprazole (aciphex)


Pantoprazole (protonix)


Omeprazole (prilosec)


Dexlansoprazole (Dexilant


Esomeprazole (Nexium)

Mucosal Protective Agents

Give 2 hours apart from other meds



Pepto-bismol: has direct antibacterial action against H.pylori



Cytotec: used as prophylaxis agains NSAID induced ulcers


May be used for abortion



Antacids (mylanta, maalox, MOM)

H.Pylori Combo therapies

2 antibiotics + PPI or bismuth



MOC:


Flagyl, Biaxin, and Prilosec



AOC:


Amoxicillin, Prilosec, and Biaxin



MOA:


Flagyl, Priolsec, and Amoxicillin



Bismuth regimens require QID dosing


BMT:


bismuth, flagyl, and tetracycline



BMT + Prilosec



Antiulcer for 3-7 weeks to ensure proper healing of ulcer and symptom relief



Duodenal: prilosec


H2 blockers


Urgent Care/ Emergent Management of PUD

CBC


PT/PTT


BMP



O2


Endoscopy


Urinary catheter


NG tube


NPO


IV H2 blockers


GI/surgery eval

GERD

back flow (reflux) of gastric contents into the esophagus



Incompetent lower esophageal sphincter



delayed gastric emptying

S/S GERD

retrosternal "burning"


bitter taste in mouth


belching


hiccoughs


dysphagia


excessive salivation


frequently occurs at night and/or recumbent position


may be relieved by sitting up, water, food, antacids

Diagnostics for GERD

EGD referral


rule out cancer


Barrett's esophagus


PUD

Management for GERD

elevate head of bed


avoid caffeine, alcohol, spices, peppermint


stop smoking


weight reduction if needed



Antacids PRN



H2 blockers (INES)


PPI (ZOLES) if H2 ineffective



GI surgical consult PRN

Gastroenteritis

n/v


diarrhea


cramping



no need for antibiotic unless bacteria present



bowel sounds hyperactive



supportive care


fluids, rehydration


clear liquids progressively


no anti motility drugs so the bug can get out



Traveler's diarrhea prophylaxis

Pepto-Bismol

Diverticulitis

inflammation or localized perforation of the diverticula with abscess formation



more common in women



higher incidence in those with low dietary fiber

S/S Diverticulitis

mild to moderate aching abdominal pain in LLQ



constipation or loose stools



n/v

PE Diverticulitis

low grade fever


LLQ tenderness to palpation


perforation may present with more dramatic and peritoneal signs

Lab/Diagnostics for Diverticulitis

mild/mod leukocytosis


elevated ESR


stool + heme in 25% of cases


sigmoidoscopy may show inflamed mucosa


might consider CT to evaluate abscess


Management for Diverticulitis

NPO dependent upon condition



Refer for IV fluids for hydration


GI/surgery consult

IBS

Lower abdominal pain and alternating diarrhea and/or constipation



greater incidence among women

S/S IBS

abdominal cramping


abdominal pain relieved by defecation


may be preoccupied with bowel symptoms


changes in stool consistency and/or pattern


dyspepsia


fatigue


anxiety and/or depression are common

Diganostics of IBS

sigmoidoscopy


barium studies


rectal exam

Management of IBS

emotional support


recommend high fiber


SSRIs for patients who are depressed


antidiarrheals


antidepressant

Choleycystitis

inflammation of the gallbladder



>90% of cases gallstones present

S/S Choleycystitis

often precipitated by a large or fatty meal


sudden appearance of steady, severe pain in epigastrium or right hypochondrium


vomiting my bring relief

PE Choleycystitis

Murphy's sign: deep pain on inspiration while fingers are placed under right rib cage



RUQ tenderness to palpation


muscle guarding and rebound pain


fever

What is gold standard for diagnosing cholycystitis?

Ultrasound

Management of choleycystitis

pain management



Acute:


refer for NGT


IV antibiotics


GI/surgery consult

Bowel Obstruction

blockage of intestinal lumen impeding passage of bowel contents

Causes of Bowel obstruction

hernia


adhesions


volvulus


tumors


fecal impaction


heus (functional obstruction)

S/S Bowel obstruction

cramping periumbilical pain intitally


pain becomes constant and diffuse


vomiting within minutes of pain (proximal block)


vomiting within hours of pain (distal block)


unable to pass stool/gas

Management of bowel obstruction

refer for fluid resucitation and NGT suction


broad spectrum abx


GI/surgery consult

Ulcerative colitis

diffuse mucosal inflammation of the colon



Involves the rectum and my extend upward involving the whole colon

S/S Ulcerative colitis

bloody diarrhea


Lab/Diagnostics for Ulcerative colitis

negative stool studies


sigmoidoscopy to establish diagnosis

Management for Ulcerative colitis

Mesalamine (Canasa) suppositories or enemas


Hydrocortisone suppositories or enema

Colon cancer

Increased incidence:


family history


other adenocarcinomas


high fat or refined carb diets


polyps


IBS

S/S colon cancer

often asymptomatic until complications



change in bowel habits


thin stools


weight loss

Diagnostics for colon cancer

possible + guiac


colonoscopy


CBC

Management of colon cancer

surgical consult


subsequent oncology consult


supportive care

Appendicitis

inflammation of appendix



if untreated, gangrene and perforation may develop in 36 hours



18-36 years of age

S/S Appendicitis

vague colicky umbilicus pain


after several hours pain goes to RLQ


nausea with 1-2 episodes vomiting


pain worse and localized with coughing

PE Appendicitis

RLQ guarding with rebound tenderness


Psoa's sign


Obturator sign


Positive Rovsing's sign


low grade fever

Psoa's sign

pain with right thigh extension


Obturator's sign

pain with internal rotation of the flexed right thigh

Rovsing's sign

RLQ pain when pressure is applied to the LLQ

Lab/Diagnostic for Appendicitis

CT

Management for Appendicitis

refer for surgery and pain management