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14 Cards in this Set
- Front
- Back
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Plumer Vinson syndrome
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Dysphagia, glossitis, iron deficiency anemia
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Topical Sprue
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Responds to antibiotics
Affects entire small bowel |
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Whipple's disease
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Infection with Tropheryma whipplei (gram +); PAS-+ foamy macrophages in intestinal lamina propria, mesenteric nodes. Cardiac symptoms, arthralgias, neurologic symptoms (CAN)
Old men with foam in a CAN |
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Celiac sprue
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Autoantibodies to gliadin, distal duodenum or jejunum
HLA-DQ2, 8, northern European descent. Anti-endomysial, anti-tissue transglutaminase used for screening. T-cell lymphoma, dermatitis herpetiformis |
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Lactase deficiency
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Symptoms + glucose rises <20 mg/dL
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Abeta lipoproteinemia
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Decrease synthesis of apoplipoprotein B --> can't make chylomicrons --> decreased synthesis of cholesterol, VLDL in blood --> fat accumulates in intereocytes.
In early childhood see malabsorption and neuro problems |
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Acute gastritis (erosive)
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Causes: stress
NSAIDS Alcohol Uremia Burns (Curling's = decreased plasma volume --> sloughing off of mucosa) Brain injury (Cushing's --> increased vagal stimulation --> increased Ach --> increased H+ production) |
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Type A Chronic gastritis
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Autoimmune against parietal cells, pernicious anemia, achlorhydia.
Body |
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Type B Chronic gastritis
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H.pylori, increased risk of MALT lymphoma
Antrum |
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Menetrier's Disease
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Gastric hyptertrophy with protein loss, parietal cell atrophy, increased mucous cells. Precancerous
Hypertrophied rugae |
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Stomach cancer
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Adenocarcinoma
Acanthosis nigricans Lesser curvature for intestinal SMJ nodule = subcutaneous periumbilical metastases |
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extraintestinal manifestastions of Crohn's
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migratory polyarthritis, erythema nodosum, ankylosing spondylitis, uveitis, kidney stones
Tx: corticosteroids, azathriprine, methotrexate, infliximab, adalimumab |
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Ulcerative colitis
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Pyoderma gangrenosum, primary sclerosing cholangitis, ankylosing spondylitis, uveitis
Tx: sulfasalazine, 6-mercaptopurine, infliximab, colectomy |
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Zenker's diverticulum
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Herniation of mucosal tissue at Killian's triangle between thryopharyngeal and cricopharyngeal parts of the inferior pharyngeal constrictor.
Halitosis, dysphagia, obstruction |
