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9 Cards in this Set

  • Front
  • Back
H pylori / PUD treatment
Only tx c documented +
1. PPI/H2 blocker x 7-14 d
2. Clarithromycin x 7-14d
3. Amox x 7-14d
4. Antacids prn
H2 blockers
Used in PUD/GERD
-"dine" drugs (cimetidine, famotidine, ranitidine, nizatindine).
-inhibit histamine binding to H2 receptors - decrease acid secretion
-QD-BID dosing
-relief w/in 2 wks
Proton pump inhibitors
-PUD/GERD tx
-"zole" (esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole)
-decrease acid secretion almost completely leading to fast relief
-faster ulcer healing than c H2 blockers.
-can use for years
Stepwise GERD tx
1. Mild s/s: lifestyle changes
2. Decrease acid production: antacids + H2 blockers OR PPIs
3. Promotility therapy for delayed gastric emptying/persistent s/s: metoclopramide (Reglan), bethanechol (Urecholine) -
many SE's to these drugs.
4. Antireflux surgery: nissen fundoplication, endoscopic suturing - 30-40% still need to use PPI
substances/conditions that decrease LES tone (GERD)
Chol/fat, chocolate, spicy, acidic food, peppermint, caffeine, tobacco, etoh.
tight clothes, obesity, ascities, preg, CNS dz, hiatal hernia, DM, others
Meds that decrease LES tone
1. Smooth muscle relaxants (theophyline, nitrates, CCB's -verapamil/nifedipine).
2. progesterone
3. nicoteine-transdermal
4. diazepam
5. meperidine
6. anticholinergics-atropine, scopalamine, belladonna
Meds to avoid in GERD
Meds that can injure esophageal mucosa: tetracyclines, quinidine, wax-matrix KCl tablets, nsaids
Oral Rehydration Therapy
-For mild/mod dehydration
-Resume feeding after rehydration complete
-Infants: <2yr rapid rehydration in 4-6hr followed by diluted forumla/milk
-Kids>2yr: rice cereal, bananas, potatoes, yogurt, lean meats
-adult: complex cho's, lean meat, yogurt, fruit, veg
-added fluids after each stool: <2yr-50-100cc, 2-10yr-100-200cc, >10yr ad lib.
-ORT: Hydra-Lyte, Rehydralyte, Pedialyte, Infalyte, Ricelyte, etc.
Risk factors for cholelithiasis
A: age (old)
B: body habitus (obese, rapid wt loss)
C: childbearing (preg)
D: drugs (fibrates, OCPs, estrog/progesterones
E: ethnicity (Pima Indian, scandinavian)
F: family hx (maternal hx stones)
G: gender (female)
H: hyperalimentation (TPN, fasting)
I: ileal/metabolic (Crohn's, DM, etoh cirrhosis, high triglycerides)