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11 Cards in this Set
- Front
- Back
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What are the 1st and 2nd leading causes of dementia?
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Alzheimer's disease 60%
vascular dementia 20% |
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What are the major risk factors for dementia?
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Advanced age-older than 80
Family history Apolipoprotein E status Others: Limited education Head trauma Episodic depression or personality disorder Autosome dominant trans of mutated chromosome 21 |
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What is the first cognition loss with dementia?
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Recent memory loss
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What are the 3 stages of Alzheimer's?
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Mild: Minor changes in memory and language
Moderate: Many behavioral domains are involved Severe:All intellectual abilities are markedly impaired and motor dysfunction emerges |
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What are some required laboratory studies to diagnose Alzheimer's
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CBC
Serum electrolytes (including calcium) Glucose BUN and creatinine Liver function tests Thyroid function tests Vitamin B12 level RPR |
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What are some focal neurological signs assoc. with vascular dementia?
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Extensor plantar responses
Pseudobulbar palsy Gait abnormalities Exaggeration of DTR’s Weakness of an extremity |
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What are the main features of Lewy Body dementia?
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dementia features overlapping with those of Alzheimer's disease
Features of Parkinson's disease Fluctuation in severity of condition on a day-to-day basis Early development of hallucinations |
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Degeneration of the cortical areas with formation of abnormal structures inside nerve cells suggests?
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Lewy Body Dementia
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Acetylcholine loss and amyloid deposits are characteristic of this disease
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Alzheimer's
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Name 2 Acetylcholinesterase Inhibitors used to treat Alzheimer's
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Donepezil
Rivastigmine |
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What other drugs are used to treat Alzheimer's?
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NSAIDS
Estrogens Antioxidants: Vit E, Selegiline |
