Genitourinary Drugs (Kidney, Ureter, Bladder, Genitalia)

Front 1

3 Pathways that may cause pseudohermaphrodidism in males:

Back 1

1) making too much testosterone or fat (more testosterone available to be aromatized, or more sites for aromatization)

2) desensitize DHT receptors (so that the only pathway testosterone has is to be aromatized to fat)

3) inhibit actions of 5 alpha reductase

Front 2

Examples of drugs that making too much testosterone or fat

Back 2

1) spirinolactone
2) ketoconazole

Front 3

Examples of drugs that desensitize DHT receptors

Back 3

1) Flutamide, bicalutamide
2) Cyproterone

***these can be used to treat prostate cancer

Front 4

Examples of drugs that inhibit actions of 5 alpha reductase

Back 4

Finasteride

***can be used to treat male pattern baldness, BPH, prostate cancer

Front 5

DOC for chlamydia

Back 5

doxycicycline

Front 6

DOC for gonorrhea

Back 6

ceftriaxone

Front 7

DOC for actinomyces

Back 7

penecillin

Front 8

clues for actinomyces causing the STD

Back 8

-oral flora
-IUD

Front 9

Treatment of BPH
1st line
2nd line

Back 9

1st line: alpha-1 selective blockers (loosen urinary sphincter)
-terazosin
-doxazosin
-tamsulosin
2nd line: 5 alpha reductase inh
-finasteride

Front 10

DOC for pt w HTN 2/2 BPH

Back 10

terazosin

Front 11

treatment of urge incontinence in
1) adults
2) kids

Back 11

1) Anticholinergics:
-oxybutyrin
-flavoxate
2) TCA's for kids
(have anticholinergic properties)
-imipramine

***train bladder to be able to hold more volume again

Front 12

treatment for stress incontinence

Back 12

alpha agonists
- pseudoephedrine

***recommend wt loss, Kegels, and diapers or pads
***may require surgery if severe

Front 13

treatment for overflow incontinence 2/2 neurogenic bladder

Back 13

Cholinergics
-Bethanacol
-Carbacol
-....stigmine

Front 14

treatment for overflow incontinence 2/2 obstruction

Back 14

surgery

Front 15

dx of overflow incontinence

Back 15

PVR > 100cc

Front 16

DOC for UTI and cystitis in non-preggo

Back 16

TMP/SMX

Front 17

DOC for pyelo in a non-preggo

Back 17

cipro

Front 18

DOC for UTI and cystitis in preggo

Back 18

DOC: nitrofurantoin
can also use: amoxacillin, ampicillin

Front 19

DOC for pyelo in preggo

Back 19

ceftriaxone

Front 20

Ballanitis?
Rx for ballanitis?

Back 20

infxn on lymph node or glans penis
Rx: anti-staph
-Nafcicillin
-Oxicillin
-Cloxacillin
-Dicloxacillin

Front 21

What is urethritis?

Back 21

STD travelled to urethre (dysuria)

Front 22

What is the criteria for using one-dose treatments for STDs?

Back 22

must be asxtic!

Front 23

Rx for PCKD
-adult onset (30-140
-infant onset

Back 23

adult onset: transplant
intant onset: supportive (self-limiting)

Front 24

fluid type in volume resuscitation for
1) kids
2) dehydrated kids
3) adults
4) dehydrated adults
5) symptomatic hypOna?
6) ANYONE who is hypOtensive

Back 24

1) D5 1/4 NS
2) D5 1/2 NS
3) D5 1/2 NS
4) D5 NS
5) 3% (hypertonic) saline, til you get to Na >120.
6) D5 NS

Front 25

How do you calculate fluid replacement in a dehydrated pt,
MAINTANCE ONLY?

Back 25

4, 2, 1 rule

1st 10 kg: 4cc/kg/hr
2nd 10kg: 2cc/kg/hr
rest of kg: 1cc/kg/hr

Front 26

Once you've calculated maintanance fluids, how do you calculate volume resuscitation in pt with ONGOING FLUID LOSS?

Back 26

in's must match out's

outs= excretion= urine flow x urine concentration

Front 27

How do you calculate fluid replacement in a BURN pt?

Back 27

4cc NS/kg/% burned areas

Front 28

Rule of nines

Back 28

Head and neck= 9%
Each arm= 9%
front of torso= 18%
back of torso= 18%
ea lower extremity= 18%
genitalia= 1%

Front 29

4 substances we can use to measure ECF

Back 29

1) inulin (best)
2) Cr
3) mannitol
4) sulfate

Front 30

2 substances we can use to measure plasma

Back 30

1) radio iodinated serum Albumin
2) Evans blue

Front 31

once you've calculated maintanance fluids for a burn pt, how do you manage the infusion rate?

Back 31

give 1st 1/2 of fluid requirement over the 1st 8 hrs

give 2nd 1/2 of fluid requirement over the next 16 hrs

Front 32

3 drugs that cause ATN

Back 32

-amphoticerin B
-cisplatin
-aminoglycosides

Front 33

3 drugs that cause AIN

Back 33

-PCN
-NSAID
-cephalosporin

Front 34

pain med for kidney stones

Back 34

morphine

Front 35

pain mgmnt for ANY abdominal pain

Back 35

meperidine (does not contract sphincter of Oddi like most pain meds)