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18 Cards in this Set
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GATA-4 expression in canine testicular tumors?
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Sertolicelltumors: diffuse nuclear and weak cytoplasmic staining
LCT: strong diffuse nuclear, weak granular cytoplasmic staining GCT negative sex-cord stromal cells of germcell-stromal cell tumor positive |
vetpath 46:893-896 2009
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Prevalence of canine testicular tumours?
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27% one or more testicular tumours
50% interstitial cell tumur 42% seminoma 8% sertolicell tumors no ass. age-tumor no clinical signs 31% more tumor types: mostly ICT/SEM |
comp path 2008, vol 138, 86-89
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Capillary hemangiomas of the scrotum and testicle in boars.
IHC for hemangiomas? Is testicular or scrotal hemangioma more common? Other tumors concurrent? |
vimentin and factor VIII +++, SMA ++ occasionally in vessel walls
Scrotum hemangiomas: frequent, testicular rare. concurrent: intratubular germ cell tumor (1) and sertolicell tumor (1) |
CP 2008, vol 139:4, 177-186
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Feline endometrial adenocarcinoma.
What markers are changed? Evidence for epithelial-mesenchymal transition? Defined by which markers? |
Cyclooxygenase-2 is upregulated,
progesterone receptor is downregulated. No evidence for epithelial-mesenchymal transition: E-cadherin not altered, Beta-catenin not altered (losing and nuclear translocation are features of e-m resp.) |
CP 2009: 140(4): 254-259
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About siamese twins, what do the following terms mean?
- thoracopagus - omphalopagus -cephalopagus - ischiopagus - Parapagus - craniopagus -pygopagus - rachipagus |
- united ventrally at the chest
- '' ''' at the abdomen - '' ''' at head and chest - '' '' at the pelvis - united laterally: dicephalus: 1 body, 2 heads, diproposus: 1 body, 2 faces - united at the heads - united caudally - dorsally at the spine. |
JWD 44, 177-180 (2008)
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Metastatic tumors to the adrenal glands in domestic animals.
1. % in dogs, cats, horses, cows? 2. most associated tumors? 3. % of tumors in adrenals that are metastatic in dog, cat horse cow? |
1. dog 20%, cats 15%, horse 27%, cow 30%
2. dog: pulmonary, mammary, prostatic, gastric, pancreatic carcinoma and melanoma. horse: hemangiosarcoma and melanoma cats and cattle: only lymphoma data. 3. dogs 26%, cat 60%, horse 26%, cow 55%. |
Vet pathol 42: 52-58 (2005)
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Canine ovarial epithelial and granulosa cell tumors.
IHC differences? |
1. granulosa cell tumor: cytokeratin-7 - and inhibin-α +, ovarial epithelial: vice versa.
Vimentin both +/- (variable). |
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PCV2 intrauterine infection via spiked semen insemination.
1. Lesions in piglets of sows that became pregnant? 2. Organ affected? 3. PCV2 antigen found where? |
1. live and viremic, mummified (42-105 day of gestation), stillborn.
2. heart of the fetuses: 2-3 times enlarged with irregular pale streaks with degeneration and fibrosis. 3. 88% of myocardium of live, 100% of stillborn and mummified fetuses. |
Vet pathol 46: 707-716 (2009)
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Transplacental infection with BVDV types 1b and 2 in calves.
1. Lesions in which organs and infection at with gestational age? 2. Viral antigen in which cells? 3. Expression of hypoxia-inducible factor-1α, inducible nitric oxide synthase (iNOS) adn phospho-p38α mitogen-activated protein kinase (MAPK)? |
1. Brain, liver, and spleen, only at 75-85 days infection, and retrievel at 190 days.
2. viral antigen in neurons, oligodendrocyte precursors and infiltrating macrophages. 3. HIF-1α normal/slight +, iNOS and MAPK +, also neuronal apoptosis. |
CP 138, 72-85, (2008)
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Cows and fetuses experimentally infected with Brucella abortus.
1. most significant lesions in cows? 2. most significant lesions in aborted fetuses? 3. Other lesions in cows and calves? |
1. necrotizing and suppurative placentitis and lymphohistiocytic mastitis.
2. fibrinous pleuritis, pericarditis and neutrophilic bronchopneumonia. 3. Cows: endometritis, lymphoid hyperplasia in spleen (more in cows with viable calves). Calves: perisplenitis and perihepatitis, hepatitis and splenitis, lymphadenitis. |
CP 140, 149-157 (2009)
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Ureaplasma diversum infection in destructive polyarthropathy in bovine fetuses.
1. Which joints where most affected? 2. Lesions? 3. Lesions in other organs (2)? 4. Other diseases caused by Ureaplasma diversum? |
1. hips, stifles, shoulders.
2. irregular reduction of cartilage thickness, fibrovascular tissue and sometimes inflammatory cells and fibrin. 3. placentitis, mild lymphoplasmacytic conjunctivitis. 4. Granular vulvovaginitis - balanoposthitis - last trimester abortion with fibrosis, necrosis, vascultis, lymphoplasmacytic cuffing peribronchiolar, lymphopl. conjunctivitis -stillbirth/weak calves. |
Vet pathol 46, 269-272 (2009)
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Lesions of infection with the following Parachlamydia and Chlamydia-like abortion?
- Chlamydophila pecorum -Cp. abortus - Waddlia chondrophila - Parachlamidia acanthamoebae - Piscichlamidia salmonis. |
- abortion, conjunctivitis, encephalomyelitis, enteritis, pneumonia and polyarthritis in cattle
- abortion in goat, sheep - abortigenic in cattle - abortigenic in cattle, also sheep/goat: necrotizing placentitis - gill epitheliocystis in Atlantic salmon |
EID 13, 1904-1907 (2007)
EID 14, nr 12 (2008) |
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Tetrapterys multiglandulosa abortion and neonatal mortality in sheep.
Lesions in fetuse? |
- Abortion between days 110-134, or born weak with nervous signs, but recovered.
- Anasarca - cardiac fibrosis and status spongiosus of the nervous system. |
Vet pathol 46: 960-965 (2009)
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Tularemia in sheep.
1. causative agent? 2. Abortion rate? 3. Fetal lesions? |
1. Fransicella tularensis
2. 0,6% to 475 3. pinpoint necrosis in spleen, liver, and lung. |
JVDI 20, 508-513 (2008)
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Brucella melitensis in naturally occuring abortion in sheep.
1. % of abortions with B. melitensis antigens? And which organs? 2. Antigen labelling in lung and liver? 3. Gross? 4. Histo? |
1. 30%: of these Ag in lung (225), spleen (12%), liver (19%), kidney (5%).
2. cytoplasm of macrophages and neutrophils, and extracellular in cellular debris in lung. Cytoplasm of macrophages and Kupffer cells, and extracellular in portal infiltrates in liver. 3. subcutaneous edema and blood-tinged fluid in body cavities. 4. Bronchopneumonia, moderate periportal leukocyte infiltration and intrasinusoidal neutrophils in fetal liver. |
JVDI 20, 803-806 (2008)
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Foot-and-mouth disease infection and death in fetal lambs.
1. Tissue tropism in lambs? 2. Cytokine response, mainly in heart muscle? Early and somewhat later? |
1.cardiac and skeletal muscles.
2. Early response anti-viral cytokines: IFN-α and IFN-β, later response (7-18 dpi) pro-inflammatory cytokines: IFN-γ, TNF-α, and IL-1α. |
CP 138, 108-120 (2008)
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BVDV infection and abortion in goats.
1. Fetal organs most affected? 2. Virus antigen via IHC in which tissues (4)? Uncommonly in which tissues (5)? Not in which tissues (3)? |
1. placentitis, encephalitis, myocarditis, and thymic depletion.
2. placenta>thymus> heart> brain. uncommonly: skin, liver, kidney, lung, trachea. Not: spleen, nasal turbinate, thyroid. |
Vet pathol 45, 54058 (2009)
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BVDV abortion in goats housed with PI cattle.
1. lesions of BVDV-2a infections? 2. Histo of placental and myocardial lesions? |
1. Facial deformities : brachygnathia inferior and prognathia, mild placentitis, mummification, myocarditis, thymic depletion, encephalitis and choroid plexitis.
2. Histo placenta: necrosis of trophoblastic epithelium, mononuclear stromal infiltrate and necrosis of deep stromal vessels. Histo myocarditis: multifocal lymphohistiocytic infiltrate with scattered small areas of myocardial necrosis |
Vet pathol 46, 45-53 (2009)
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