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27 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
cell line
genetically identical cells that divide indefinitely and can be cultured in the laboratory
186
centiMorgan
another name for map unit
173
coefficient of coincidence
ratio of observed double crossovers to expected double crossovers
181
coupling (cis) configuration
arrangement in which two or more wild-type genes are on one chromosome and their mutant alleles are on the homologous chromosome; also called coupling configuration
167
deletion mapping
technique for determining the chromosomal location of a gene by studying the association of its phenotype or product with particular chromosome deletions
185
genetic map
map of the relative distances between genetic loci, markers, or other chromosome regions determined by rates of recombination; measured in percent recombination or map units
173
genetic marker
any gene or DNA sequence used to identify a location on a genetic or physical map
185
heterokaryon
cell possessing two nuclei derived from different cells through cell fusion
186
interchromosomal recombination
recombination among genes on different chromosomes
169
interference
degree to which one crossover interferes with additional crossovers
180
intrachromosomal recombination
recombination among genes located on the same chromosome
169
linkage group
genes located together on the same chromosome
162
linked genes
genes located on the same chromosome
162
lod (logarithm of odds) score
logarithm of the ratio of the probability of obtaining a set of observations, assuming a specified degree of linkage,to the probability of obtaining the same set of observations with independent assortment; used to assess the likelihood of linkage between genes from pedigree data
185
map unit (mu)
unit of measure for distances on a genetic map; 1 map unit equals 1% recombination
173
mapping function
relates recombination freqeuncies to actual physical distances between genes
183
Morgan
100 map units
173
nonrecombinant (parental) gamete
contains only the original combinations of genes present in the parents
164
nonrecombinant (parental) progeny
possesses the original combinations of traits possessed by the parents
164
physical map
map of physical distances between loci, genetic markers, or other chromosome segments; measured in base pairs
173
recombinant gamete
possesses new combinations of genes
164
recombinant progeny
possesses new combinations of traits formed from recombinant gametes
164
recombination frequency
proportion of recombinant progeny produced in a cross
166
repulsion (trans) configuration
arrangement in which each chromosome contains one wild-type (dominant) gene and on mutant (recessive) gene; also called repulsion
167
somatic-cell hybridization
fusion of different cell types
186
three-point testcross
cross between an individual heterozygous at three loci and an individual homozygous for recessive alleles at thoe loci
175
two-point testcross
cross between an individual heterozygous at two loci and an individual homozygous for recessive alleles at those loci
174