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16 Cards in this Set
- Front
- Back
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What are the 6 ways that the genetics of human behavior have been studied?
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- twin studies
- adoption studies - linkage analysis - human genome project - mouse models - candidate genes |
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What are candidate genes?
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- gene researchers believe may be associated with a specific disease
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Which receptor may be linked to alcoholism?
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- dopamine D2 receptor (pleasure-seeking center)
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If an identical twin has schizophrenia what is the likelihood that the other twin will get it? What if they were fraternal twins? Just siblings?
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- 48%
- 17% - 9% |
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25% of people with which syndrome develop schizophrenia?
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- DiGeorge syndrome
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What is the likelihood of the general population getting schizophrenia vs secondary relative (cousin, aunts)?
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- 1%
- 2% |
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Autism is characterized by impairments in which 3 domains?
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- social interaction
- language - range of interests/activities |
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What is the reported recurrence risk for a sibling if the child with autism is female? male? 2 or more children in a family with autism?
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- 4% vs 7%
- 35% |
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What are the 7 main genetic syndromes that are associated with autism?
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- fragile X
- Rett - Angelman - Prader-Willi - Smith-Lemli-Opitz - Tuberous sclerosis - Sotos |
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About what percent of children with Down syndrome have autism?
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- 7%
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25% of individuals with which disease have autism?
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- Tuberous sclerosis
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What are the red flags for autism at 6,9, and 12 months?
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6: no smile/joyful expression
9: no sharing of sounds/smiles/expressions 12: no babblings/ gestures/ reaching/ waving |
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Microarry studies, fragile X studies, and MeCP2 testing has what percent diagnostic yield for ASDs evaluations?
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- 10%
- 5% - 5% (females only) |
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What evaluations studies should be done prior to bringing a child with suspected autism disorder into a geneticist?
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- hearing evaluation
- fragile X testing/chromosomes |
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What percent of children with Fragile X have autistic behaviors?
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- 50%
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Which syndrome is associated with a period of normal development and then a decline?
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- Rett syndrome
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