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62 Cards in this Set
- Front
- Back
traits for model organism
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• Short generation time
• Large number of offspring • Easy and inexpensive to maintain • Phenotypes that occur in other organisms • Sequenced genome |
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categorical traits at one extreme or the other
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discrete
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phenotype ratio for monohybrid cross
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3:1 dominant to recessive
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variant form of a gene
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allele
ex) tallness or shortness |
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During gamete formation, the two
alleles separate (segregate) randomly, with each gamete having an equal probability of either allele |
law of segregation
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F2 generation phenotype ratio in dihybrid cross
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9:3:3:1
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The alleles for one gene can segregate
independently of alleles for other genes |
law of independent assortment
ex) whether gamete gets W or w it doesn't influence if it will get G or g |
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-the most commonly occurring
characteristic in nature |
wild type
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-any allele other than wild-type
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mutant
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this rule is used for mutually exclusive events
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sum rule
key word: or |
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rule used for independent outcomes
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product rule
key word: AND |
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if calculated chi square test is ___ than critical value, then ___ the null hypothesis
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less; fail to reject
- The data are consistent with the genetic model used to generate the expected values. |
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true or false- prokaryotes have no true nucleus, no nuclear membrane
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true
- divide by binary fission, DNA located in nucleoid |
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type of chromatin that is more tightly packed & cannot transcribe genes
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heterochromatin
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type of chromatin that is more loosely packed, & may be transcriptionally active
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euchromatin
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where sister chromatids attach
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centromere
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centromere in middle
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metacentric
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centromere at tip of chromosome
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telocentric
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centromere near end but not at tip
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acrocentric
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slightly off-center centromere
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submetacentric
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homologous pairs of chromosomes arranged from largest to smallest
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karyotypes
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chromosomes that are same size, shape, have same banding pattern & same genes
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homologous chromosomes
- may have different alleles |
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what are phases of cell cycle
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G1, S, G2, M
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MPF is made up of what 2 proteins
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cyclin b & CDC2
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true or false- M checkpoint is a cyclin regulated checkpoint
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false
- spindle attachment checkpoint- make sure spindle is attached correctly |
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in S phase it is __ n and __ c
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2n and 4c
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each daughter cell and end of mitosis is __ n and __ c
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2n and 2c
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what happens in prophase of mitosis
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- chromosome condensation
- nuclear envelope breakdown - disappearance of nucleolus - chromosomes replicate - centrosomes appear |
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attach to kinetochore proteins true or false
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true
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these microtubules don't attach to kinetochores & interact w/ microtubules from opposite poles
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polar microtubules
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phase where chromosomes move to metaphase plate, each chromosome has its sister chromatids attached to opposite poles, chromosomes not in pairs
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metaphase (mitosis)
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phase in mitosis where sister chromatids separate & move toward poles
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anaphase
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role of mitosis in life cycle is:
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division of somatic cells
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Meiosis I is ___ division while meiosis II is __ division
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reductional; equational
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stage in prophase I where chromosome condensation & bouquet stage occurs
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leptonema
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stage in prophase I where pairing of homologous chromosomes to form bivalents
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zygonema
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stage in prophase I where synapsis, homologs are held together by synaptonemal complex, & crossing over occurs
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pachynema
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stage in prophase I where tetrads & synaptonemal complex disintegrates
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dipolema
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stage in prophase I where nuclear envelope breaks down & chiasmata migrate toward tips of chromosomes
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diakinesis
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when chiasmata migrates toward tips of chromosomes its called
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terminalization
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___ complex is proteinacous structure that holds homologs together
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synaptonemal
- 2 lateral elements & 1 central element |
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- physical exchange of DNA between homologous chromosomes
- reciprocal exchange - breaking & rejoining DNA - covalent bonds broken & reformed |
crossing over
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phase in meiosis where homologous pairs allign at metaphase plate
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metaphase I
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phase in meiosis where homologs separate
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anaphase I
- both sister chromatids are attached |
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at end of spermatogenesis there are how many sperm cells
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4
all haploid |
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in bees, males are ___ and females are ___
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haploid & diplid
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___ sex has XX
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homogametic
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___ sex has XY
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heterogametic
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homologs pair in meiosis due to ___ regions
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pseudoautosomal
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gene is on the chromosome
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sex-linked inheritance
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trait is expressed in only one gender & the gene is autosomal
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sex-limited
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trait is dominant in one gender & recessive in the other
- gene is autosomal |
sex-influenced
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phenotype ratio for incomplete dominance
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1:2:1
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where one gene affects two or more phenotypes
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pleitropy
- dominance relationships may be different for each phenotype ex) sickle-celled anemia |
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in complementation, if 1 gene is involved then..
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there is non-complementation
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in complementation, if 2 genes are involved then
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complementation occurs
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if there is a lethal allele, the phenotype ratio is
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2:1
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a phenotype affected by the environment that mimics an inherited phenotype
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phenocopies
ex) rickets |
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dominant lethal mutations can occur under what 2 circumstances
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1. late onset
2. incomplete penetrance |
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who thought of preformation & homoculus
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greeks in 400-500 bc
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subdiscipline in genetics that deals with changes in allele frequencies in
populations over time |
population & evolutionary genetics
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in male plant reproductive structures are
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anther & filament
- remove anther to cross-fertilize |