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18 Cards in this Set
- Front
- Back
How many genes are there in the human genome?
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25,000
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What is the structure formed when DNA is wraped around histones?
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Nucleosomes
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Each gene is inherited in two copies
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Alleles
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The short arm
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P
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The long arm
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Q
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The 2 chromatids attached to a single centromere of a chromosome after DNA replication has occurred
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Sister Chromatid
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Ends of chromosome capped with?
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3-20 kb of TTAGGG repeats
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TAR (telomere associated repeats)
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Not used for FISH probes because these are shared among subsets of human chromosomes
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What is now used for FISH?
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Unique DNA
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-The primary constriction of the chromosome
-seen only when chromosomes are condensed -Contains alpha satellite DNA -Used as a center of movement of the chromosome during mitosis & meiosis |
Centromere
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The protein structure on either side of the centromere
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Kinetochore
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Centromere near the end of the chromosome (one arm smaller than the other)
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Acrocentric
Stalk region has rDNA |
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Centromere near the middle of the chromosome
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Metacentric
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Centromere nearer to one end than the other
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Sub-metacentric
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Lightly packed form of chromatin rich in gene structure
-G negative |
Euchromatin
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Tightly packed form chromatin that is poor in gene concentration
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Heterochromatin
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The type of heterochromatin that is never transcribed
Generally G+ |
Constitutive heterochromatin
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The type of heterochromatin that can be genetically active, but is turned off
Can be G+ or G- |
Facultative Heterochromatin
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