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18 Cards in this Set

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  • Back
How many genes are there in the human genome?
25,000
What is the structure formed when DNA is wraped around histones?
Nucleosomes
Each gene is inherited in two copies
Alleles
The short arm
P
The long arm
Q
The 2 chromatids attached to a single centromere of a chromosome after DNA replication has occurred
Sister Chromatid
Ends of chromosome capped with?
3-20 kb of TTAGGG repeats
TAR (telomere associated repeats)
Not used for FISH probes because these are shared among subsets of human chromosomes
What is now used for FISH?
Unique DNA
-The primary constriction of the chromosome

-seen only when chromosomes are condensed

-Contains alpha satellite DNA

-Used as a center of movement of the chromosome during mitosis & meiosis
Centromere
The protein structure on either side of the centromere
Kinetochore
Centromere near the end of the chromosome (one arm smaller than the other)
Acrocentric

Stalk region has rDNA
Centromere near the middle of the chromosome
Metacentric
Centromere nearer to one end than the other
Sub-metacentric
Lightly packed form of chromatin rich in gene structure

-G negative
Euchromatin
Tightly packed form chromatin that is poor in gene concentration
Heterochromatin
The type of heterochromatin that is never transcribed

Generally G+
Constitutive heterochromatin
The type of heterochromatin that can be genetically active, but is turned off

Can be G+ or G-
Facultative Heterochromatin