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4 Cards in this Set
- Front
- Back
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Hardy Weinburg equation |
* used to calculale and 'predict' certain genotype frequencies p^2 + 2pq + q^2 |
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Problems Practically Applying Hardy Weinburg |
* AR disorders - cant distinguish 'carriers' from normal * XLR disorders - can't tell between female carriers and non-carriers |
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Hardy-Weinberg Equilibrium Assumptions |
* allele frequencies don't change from one generation to another * genotype frequencies can be determined by the relative frequencies of the alleles at that locus |
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Factors Affecting the Hardy-Weingburg Equilibrium |
* Small/isolated populations & inbreeding/consanguinity * Non-random mating * Evolutionary selection * migration * altered mutation rate * heterozygote advantage * gene flow * mutational hotspots |
