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11 Cards in this Set
- Front
- Back
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Who is Fredrick Meischer (1868)?
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isolated nuclei (contains DNA). Noticed it was high in phorsphorous, acidic, and polymeric (distinct from proteins)
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Who is P. Levene (1910)?
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Incorrectly postulated that DNa consists of equal number of four nucleotides (A,T,G,C)
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Who is Chargaff (1940)?
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A = T, C = G
A + G = T + C purines = pyrmidines |
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Who is Griffith(1927)?
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Created an experiment with mice that discovered transformation (genetics passed from one bacteria to another)
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Who is Avery, MacLeod, and McCarthy?
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Isolated DNA, demonstrated that it was the factor that was transfered.
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Who is Hershey and Chase?
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Experiment demonstrated that virus transmits nuclei not protein to cell.
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Who are Meselson and Stahl (1958)?
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used sedimentation equilibrium centrifugation to prove DNA is semiconservative
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Who is Roaslind Franklin?
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Used DNA x-ray disfraction to help discover the structure of DNA
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What is the Watson-Crick Model of DNA
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1)antiparallel strains
2)polynucleotide chains coiled around central axis forming right handed double helix 3) bases stacked on one another 4) contains major and minor grooves 5) 20 A diameter 6) A = T, C = G 7) 10 base pairs long or 34 A |
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The Taylor-Woods-Hughes experiment?
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demonstrates semiconservation in tip roots of Vicia faba. Uses 3H thymidine as label.
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Who is Arthur Kornburg?
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Deterimined that DNA can be syntehsiez in presense of four dNTP, template DNA and primer, and DNA polymerase
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