Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
What weeks / embryonic stage is organogenesis |
Weeks 3-10 Teratogens most likely to disrupt organs at this stage. Prior to this teratogens tend to kill or not affect the fetus |
|
|
In X-links conditions are males or females more affected, and what proportion? |
Male Female carrier = half of males affected Male carrier = all males normal and all females carriers (males inherit the Y😃 |
|
|
Name at least one X linked dominant condition |
X-linked hypophosphataemic rickets Incontinentia pigmenti (lethal in males, as most X linked dominant are) |
|
|
No females affected in a pedigree, what’s the likely mode of inheritance? |
X linked recessive |
|
|
Mostly males affected in a pedigree - what’s the inheritance |
X linked recessive |
|
|
Mostly females affected in a pedigree with no males - what’s the inheritance? |
X linked dominant - such as X linked hypophosphataemic rickets or incontinentia pigmenti |
|
|
Males and females affected equally in a pedigree - what’s the possible mode of inheritance? |
AD or AR |
|
|
Maternal inheritance only - males and females equally affected. What’s the mode of inheritance? |
Mitochondrial inheritance - only inherited by maternal lines but affect male and female offspring equally |
|
|
Name conditions associated with mitochondrial inheritance? |
MELAS and MERFF - spread only maternally but affect male and female offspring equally |
|
|
How many pairs of chromosomes are there? |
23. One of those is sex chromosomes |
|
|
How many pairs of autos ones are there? |
22 - one pair of sex |
