Genetic Disease Prevalence

Front 1

Down's Syndrome

Back 1

1/700 to 1/1000

Chromosomal Disease

Front 2

Kliefelter's Syndrome

Back 2

1/1000 males

Chromosomal Disease

Front 3

Trisomy 13

Back 3

1/10,000

Chromosomal Disease

Front 4

Trisomy 18

Back 4

1/6000

Chromosomal Disease

Front 5

Turners Syndrome

Back 5

1/2500 to 1/10000 females

Chromosomal Disease

Front 6

Adenomatous Polyposis Coli

Back 6

1/6000

Single-Gene Disorder

Front 7

Adult Polycystic Kidney Disease

Back 7

1/1000

Single-Gene Disorder

Front 8

alpha-1 antitrypsin deficiency

Back 8

1/2500 to 1/10,000 Caucasians

Single Gene Disorder

Front 9

Cystic Fibrosis

Back 9

1/2000 to 1/4000 Caucasians

Single Gene Disorder

Front 10

Duchenne Muscular Dystrophy

Back 10

1/3500 males

Single gene disorder

Front 11

Familial Hypercholestremia

Back 11

1/500

Single Gene Disorder

Front 12

Fragile X syndrome

Back 12

1/4000 - 1/8000 males

Single Gene Disorder

Front 13

Hemochromatosis

Back 13

1/1000 Caucasians

Single Gene Disorder

Front 14

Hemophilia A

Back 14

1/5000 - 1/10,000 males

Single Gene Disorder

Front 15

Hereditary Nonpolyposis Colorectal Cancer

Back 15

1/200

Front 16

Huntington Disease

Back 16

1/20,000 Caucasians

Single Gene Disorder

Front 17

Marfan's Syndrome

Back 17

1/10,000

Single Gene Disorder

Front 18

Myotonic Dystrophy

Back 18

1/10,000

Single Gene Disorder

Front 19

Neurofibromatosis I

Back 19

1/3500 to 1/5000

Single Gene Disorder

Front 20

Osteogenesis Imperfecta

Back 20

1/5000 to 1/10,000

Single Gene Disorder

Front 21

Phenylketyluria

Back 21

1/10,000 to 1/15,0000 Caucasians

Single Gene Disorder

Front 22

Retinoblastoma

Back 22

1/20,000

Single Gene Disorder

Front 23

Sickle Cell Disease

Back 23

1/400 African Americans

Single Gene Disorder

Front 24

Tay Sach's Disease

Back 24

1/3000 Askanazi Jews

Single Gene Disorder

Front 25

Thalassemia

Back 25

1/50 South Asian and sub-Mediterranian Population

Single Gene Disorder

Front 26

Cleft Lip w/wo Cleft Palatte

Back 26

1/500 to 1/1000

Multifactorial Disorders

Front 27

Club Foot

Back 27

1/1000

Multifactorial Disorders

Front 28

Congenital Heart Defect

Back 28

1/200 to 1/500

Multifactorial Disorder

Front 29

Neural Tube Defect (spina bifida)

Back 29

1/200 to 1/1000

Multifactorial Disease

Front 30

Pyloric Stenosis

Back 30

1/300

Multifactorial Disease

Front 31

Alcoholism

Back 31

1/10 to 1/20

Adult Multifactorial Disorder

Front 32

Alzheimer's Disease

Back 32

1/10 Americans over age of 65

Adult Multifactorial Disorder

Front 33

Bipolar Affective Disorder

Back 33

1/100 to 1/200

Adult Multifactorial Disorder

Front 34

Cancer (all types)

Back 34

1/3

Adult Multifactorial

Front 35

Diabetes (type I and II)

Back 35

1/10

Adult Multifactorial

Front 36

Heart Disease and Stroke

Back 36

1/3 to 1/5

Adult Multifactorial

Front 37

Schizophrenia

Back 37

1/100

Adult Multifactorial

Front 38

Kaerns-Sayre Syndrome

Back 38

Rare

Mitochondrial Disease

Front 39

LHON

Back 39

Rare

Mitochondrial Disease

Front 40

MELAS

Back 40

Rare

Mitochondrial Disease

Front 41

MERRF

Back 41

Rare

Mitochondrial Disease