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17 Cards in this Set
- Front
- Back
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APC
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Tumor suppressor gene associated with Colon Cancer
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KRAS
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Proto-oncogene/oncogene that upregulates cell division
Associated with colon cancer |
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P53
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Tumor suppressor gene, regulates the cell cycle
Associated with colon cancer, breast, head/neck, ovarian, gastric, brain |
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RAS
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Associated with lung cancer
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EGFR
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Epidermal growth factor receptor helps cells grow |
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RAS
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A downstream messenger associated with EGFR essential for cell proliferation
Associated with lung cancer, NSCLC |
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ALK
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associated with lung cancer
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Lynch syndrome
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Germline mutation that predisposes people with colon cancer. 1 hit of 2 hit theory. |
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BRCA 1 and BRCA 2
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It is a tumor suppressor gene normally, but when turned off they are |
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HER-2
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Human epidermal growth factor receptor
Associated with breast cancer, gastric cancer |
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P53 and P16
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Tumor suppressor genes |
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CDx2
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Gene that causes de-differentiation to occur
Associated with Head/neck, gastric |
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CA 125
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Cancer Antigen 125 associated with
Ovarian cancer |
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1p/19q chromosome deletion
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Associated with brain cancer
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MGMT hypermethylation
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associated with brain cancer
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NfKB
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upregulation of RNA for damage control after injury
Associated with Lymphoma |
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Philadelphia chromosome
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translocation of the long arms of chromosome 9 and 22
Associated with CML |
