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39 Cards in this Set

  • Front
  • Back
Risk factors for atherosclerosis
1) Smoking
2) HTN
3) Hypercholesterolemia
4) DM
5) Hereditary
Claudication
Profound fatigue, aching, or crampy pain in the extremity caused by exertion
**Reproducible at constant distance
**Relieved by rest
5 P's of Peripheral Ischemia
1) Pain
2) Pallor
3) Pulselessness
4) Paresthesia
5) Paralysis
Claudication
Fatigue, aching, or crampy pain in the extremity caused by exertion
*Reproducible at constant distance
*Relieved by rest
Ischemic rest pain
Pain, burning, or tingling at rest, usually across the distal foot and arch
Gangrene
Tissue necrosis
*Blood flow inadequate to maintain tissue viability
Ankle-brachial Index (ABI)
Ankle systolic pressure divided by brachial pressure while pt is supine
*Normal = 1.1
*Claudication = 0.6
*Rest pain = 0.25
Incompressible arteries in ABI
Result from calcification, seen in diabetes and renal failure
Duplex scanning
Measures arterial obstruction via blood flow characteristics and velocity
Gold standard for vascular imaging
Angiography
% of acute arterial emboli that originate in the heart
80-90%
2/3 of thrombi of the heart arise secondary to...
Atrial fibrillation
Paradoxical emboli
Venous emboli that pass into arterial system through defects connecting right and left heart chambers
Signs of impending irreversible limb ischemia
1) Loss of sensation
2) Mottling of the skin
3) Involuntary muscle contraction
4) Loss of pressure & temp
Management of acute arterial insufficiency
Immediate heparinization
When is fasciotomy considered?
When ischemia lasts for more than 4 hours
*Relieves compartmental pressure and avoids compression of arterial and venous vessels
Complications of reperfusion of ischemic tissue
1) Lactic acidosis
2) HYPERkalemia
3) Myoglobinuria or ATN
4) Muscle edema or compartment syndrome
Atheroembolism
Sudden rupture of athersclerotic plaque
"Blue toe syndrome"
Lower extermity atheroembolism
Sharply demarcated areas of focal ischemia of lower leg or foot
Symptoms of Blue toe syndrome
1) Intense pain
2) Purplish discoloration of skin
3) Thigh and calf myalgias
Do patients with Blue toe syndrome have palpable distal pulses?
Yes
Management of Blue toe syndrome
1) Arteriography & echocardiography
2) Surgical therapy - endarterectomy
3) Heparin
MCC of stroke
Carotid artery atherosclerosis
MC site of disease in cerebral circulation
Carotid bifurcation
Transient Ischemic Attack (TIA)
Sudden onset of focal neurologic deficit that resolves completely within 24 hours
Do TIAs cause ipsilateral or contralateral deficits?
Contralateral
Amaurosis fugax
Transient loss of vision in the ipsilateral eye, secondary to obstruction of branch of ophthalmic artery
Vertebrobasilar insufficiency results in
1) Binocular vision loss
2) Drop attacks
3) Dysarthria
4) Vertigo
5) Dysphagia
6) Incoordination
Middle cerebral artery stroke leads to...
1) Contralateral hemiparesis or hemiplegia
2) Paralysis of contralateral lower part of face
3) Contralateral homonymous hemianopsia
4) Aphasia
Anterior cerebral artery stroke leads to...
1) Contralateral monoplegia
2) Sparing of face
3) Abnormalities of higher cerebral function
Used as medical therapy for prevention and treatment of CVAs when aspirin is contraindicated
Ticlopidine
MC site of disease in cerebral circulation
Carotid bifurcation
Transient Ischemic Attack (TIA)
Sudden onset of focal neurologic deficit that resolves completely within 24 hours
Do TIAs cause ipsilateral or contralateral deficits?
Contralateral
Amaurosis fugax
Transient loss of vision in the ipsilateral eye, secondary to obstruction of branch of ophthalmic artery
Vertebrobasilar insufficiency results in
1) Binocular vision loss
2) Drop attacks
3) Dysarthria
4) Vertigo
5) Dysphagia
6) Incoordination
Middle cerebral artery stroke leads to...
1) Contralateral hemiparesis or hemiplegia
2) Paralysis of contralateral lower part of face
3) Contralateral homonymous hemianopsia
4) Aphasia
Anterior cerebral artery stroke leads to...
1) Contralateral monoplegia
2) Sparing of face
3) Abnormalities of higher cerebral function
Used as medical therapy for prevention and treatment of CVAs when aspirin is contraindicated
Ticlopidine