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39 Cards in this Set
- Front
- Back
Risk factors for atherosclerosis
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1) Smoking
2) HTN 3) Hypercholesterolemia 4) DM 5) Hereditary |
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Claudication
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Profound fatigue, aching, or crampy pain in the extremity caused by exertion
**Reproducible at constant distance **Relieved by rest |
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5 P's of Peripheral Ischemia
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1) Pain
2) Pallor 3) Pulselessness 4) Paresthesia 5) Paralysis |
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Claudication
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Fatigue, aching, or crampy pain in the extremity caused by exertion
*Reproducible at constant distance *Relieved by rest |
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Ischemic rest pain
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Pain, burning, or tingling at rest, usually across the distal foot and arch
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Gangrene
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Tissue necrosis
*Blood flow inadequate to maintain tissue viability |
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Ankle-brachial Index (ABI)
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Ankle systolic pressure divided by brachial pressure while pt is supine
*Normal = 1.1 *Claudication = 0.6 *Rest pain = 0.25 |
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Incompressible arteries in ABI
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Result from calcification, seen in diabetes and renal failure
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Duplex scanning
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Measures arterial obstruction via blood flow characteristics and velocity
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Gold standard for vascular imaging
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Angiography
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% of acute arterial emboli that originate in the heart
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80-90%
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2/3 of thrombi of the heart arise secondary to...
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Atrial fibrillation
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Paradoxical emboli
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Venous emboli that pass into arterial system through defects connecting right and left heart chambers
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Signs of impending irreversible limb ischemia
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1) Loss of sensation
2) Mottling of the skin 3) Involuntary muscle contraction 4) Loss of pressure & temp |
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Management of acute arterial insufficiency
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Immediate heparinization
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When is fasciotomy considered?
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When ischemia lasts for more than 4 hours
*Relieves compartmental pressure and avoids compression of arterial and venous vessels |
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Complications of reperfusion of ischemic tissue
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1) Lactic acidosis
2) HYPERkalemia 3) Myoglobinuria or ATN 4) Muscle edema or compartment syndrome |
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Atheroembolism
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Sudden rupture of athersclerotic plaque
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"Blue toe syndrome"
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Lower extermity atheroembolism
Sharply demarcated areas of focal ischemia of lower leg or foot |
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Symptoms of Blue toe syndrome
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1) Intense pain
2) Purplish discoloration of skin 3) Thigh and calf myalgias |
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Do patients with Blue toe syndrome have palpable distal pulses?
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Yes
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Management of Blue toe syndrome
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1) Arteriography & echocardiography
2) Surgical therapy - endarterectomy 3) Heparin |
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MCC of stroke
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Carotid artery atherosclerosis
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MC site of disease in cerebral circulation
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Carotid bifurcation
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Transient Ischemic Attack (TIA)
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Sudden onset of focal neurologic deficit that resolves completely within 24 hours
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Do TIAs cause ipsilateral or contralateral deficits?
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Contralateral
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Amaurosis fugax
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Transient loss of vision in the ipsilateral eye, secondary to obstruction of branch of ophthalmic artery
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Vertebrobasilar insufficiency results in
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1) Binocular vision loss
2) Drop attacks 3) Dysarthria 4) Vertigo 5) Dysphagia 6) Incoordination |
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Middle cerebral artery stroke leads to...
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1) Contralateral hemiparesis or hemiplegia
2) Paralysis of contralateral lower part of face 3) Contralateral homonymous hemianopsia 4) Aphasia |
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Anterior cerebral artery stroke leads to...
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1) Contralateral monoplegia
2) Sparing of face 3) Abnormalities of higher cerebral function |
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Used as medical therapy for prevention and treatment of CVAs when aspirin is contraindicated
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Ticlopidine
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MC site of disease in cerebral circulation
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Carotid bifurcation
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Transient Ischemic Attack (TIA)
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Sudden onset of focal neurologic deficit that resolves completely within 24 hours
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Do TIAs cause ipsilateral or contralateral deficits?
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Contralateral
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Amaurosis fugax
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Transient loss of vision in the ipsilateral eye, secondary to obstruction of branch of ophthalmic artery
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Vertebrobasilar insufficiency results in
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1) Binocular vision loss
2) Drop attacks 3) Dysarthria 4) Vertigo 5) Dysphagia 6) Incoordination |
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Middle cerebral artery stroke leads to...
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1) Contralateral hemiparesis or hemiplegia
2) Paralysis of contralateral lower part of face 3) Contralateral homonymous hemianopsia 4) Aphasia |
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Anterior cerebral artery stroke leads to...
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1) Contralateral monoplegia
2) Sparing of face 3) Abnormalities of higher cerebral function |
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Used as medical therapy for prevention and treatment of CVAs when aspirin is contraindicated
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Ticlopidine
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