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22 Cards in this Set

  • Front
  • Back

Inflammare

Latin term, to set on fire

Inflammation

A protective and defensive rxns of the body

Irritant

Pertains to any cause of inflammatory reactions

Aulus Cornelius Celsus

Long regarded as the author of the 4 cardinal signs of inflammation

Redness - Rubor

Hyperemia of vessels - ↑ Blood flow

Swelling - Tumor

Accumulation of fluid/s, inflammatory cells and cellular debris on irritated area

Heat - Calor

Delivery of warm blood to the irritated area

Pain - Dolor

Stimulation of sensory nerve endings

Bradykinin and Prostaglandin

Inflammatory mediators

Rudolf Virchow

Author of the 5th Cardinal Sign

Loss of Function - Functio laesa

Inhibition of movement - Pain and Swelling

Vascular, Exudative, Proliferative

Major changes during Inflammatory Process

Vascular Changes

Increase capillary permeability

Exudative Changes

Delivery of fluid, inflammatory cells and cellular debris to the irritated area

Proliferative Change

Described by fibroplasia, angiogenesis/neovascularization

Exudative Inflammation

Exudate is present, ↑ in protein and ↑ cellular debris

Serous Inflammation

Serous exudate is present, ↑ serum but ↓ in inflammatory cells

Purulent/Suppurative

Pus exudate is present ↑ Neuttophils, dead bacteria, RBC and cellular debris

Fibrinous

Coagulated protein exudate from plasma fibrinogen is present

Catarrhal/Mucopurulent

Has copious discharge of mucus and epithelial debris from mucosa

Diphtheritic

Fibrinous exudate is present and is firmly attached on underlying epithelium

Granulomatous

Present in chronic type inflammation, macrophages predominate