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10 Cards in this Set

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Insufficient secretion of vasopressin causes:

Diabetes Insipidus

What is Diabetes Insipidus?

Body loses ability to concentrate urine.

Oxytocin function

Uterine contractions, lactation.

2 major forms of diabetes insipidus?

1. Central (neurogenic, pituitary, neurohypophyseal) characterized by decreased secretion of ADH (also referred to as arginine vasopressin AVP).


2. Nephrogenic DI - characterized by decreased ability to concentrate urine because of resistance to ADH action in kidney.

Most common symptoms of diabetes insipidus?

Frequent urination.

What is anion gap?

[Na+] + [K+] - [Cl-] - [HCO3}

What is etiology of anion gap metabolic acidosis?

MUDPILES


Methanol Ingestion


Uremia


Diabetic Ketoacidosis


Paraldehyde Ingestion


Isoniazid Ingestion


Lactic Acidosis


Ethylene Glycol Ingestion


Salicylate Ingestion

What is the etiology of nonanion gap acidosis?

GI losses


Renal losses

Central pontine myelinolysis causes:

The most common cause of central pontine myelinolysis is a quick change in the body's sodium levels. This most often occurs when someone is being treated for low blood levels of sodium (hyponatremia) and the sodium is replaced too fast. It also can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly.

Drugs that treat fever and mechanism?

ASA, acetaminophen and ibuprofen are cyclooxygenase (COX) inhibitors that block the formation of prostaglandin E2 in the hypothalamus and effectively control fever.