Gene Therapy

Front 1

used to lacalize the Huntington's gene relative to other genetic markers

Back 1

genetic map

Front 2

a gene that has been mapped previously

Back 2

genetic marker

Front 3

the difference between the presence and absence of certain restriction enzyme sites

Back 3

restriction fragment length polymorphisms

Front 4

procedure that uses probes to identify the polymorphisms between two people - but each individual is marked individually and u just make the comparison yourself

Back 4

southern blot

Front 5

PCRs role in genetic marking of huntington disease (or any other disease)

Back 5

PCR makes copies of the gene and amplifies the gene so that we could see the number of repeats of a specific codon

Front 6

germ-line transformation

Back 6

introducing a new gene (transgene) into a fertilized egg, which means that every daughter cell will be affected and even for generations after that

Front 7

somatic cell transformation

Back 7

introducing a transgene into a regular cell like a blood, bone, intestinal cell so that it affects that cell itself but is not passe down to daughter cells

Front 8

adenovirus

Back 8

viruses that are safe bc they go into the genome of the host clel but they do not incorporate their own genes into the cell

Front 9

ti plasmid

Back 9

this is used in agrobacterium tumefaciens, for the transformation of plants

Front 10

genetic engineering of plants

Back 10

use a t-plasmid
replace the tumor gene with a desired gene and incorporate it into the cells

Front 11

what must an engineered t-plasmid have?!?!?

Back 11

promoter!!!!!

Front 12

genomics

Back 12

the effort to sequence, interpret, and compare whole genomes or various, bacteria and archaea