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21 Cards in this Set
- Front
- Back
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Prokaryotic genes are commonly groupes as
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operons
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prokaryotic transcription and translation are
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coupled
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Who controls the operon
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operator
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Operator does what
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on/off genes
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regulation of the operator is controlled by
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repressor protein
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Prokaryotic transcription has what kind of genes
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polycistronic (multiple)
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Are inducers big? And what do they do?
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their small and they bind to the repressor inhibiting its effect
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Major points for gene regulation in eukaryotic genes/
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HDAC and HAT
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WhAT does the CAP binding protein do?
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prevents 5--.3' exonuclease
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mRNA to the nucleus what get exchanged
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CAP for eIF4E
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What does the poly A tail do?
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linker decreases 3-->5 excision
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Whats function of poly A tail/
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stablizie mRNA
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lenght of poly A tail is directly correlated w
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1/2 life of mRNA
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What is an exon?
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150 nucleotides where an intron is 3500 bases
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What does alternative splicing do
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The role of alternative splicing in the perception of sounds of different frequencies. The ability to hear sounds from 50 Hz to 5000 Hz is due to the apical hair cells found within the cochlea.
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What is schmid metaphyseal chondrodyslplasia
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autosomal dom, short stature and wide irreg growth plate
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in this TGG converted to
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TAA termination codon
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Translation is initiated by
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binding of eIF4 to the CAP binding complex
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Protein stability controlled by
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ubiquitin
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Prader-WIlli syndrome
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Prader-Willi syndrome is a genetic disorder characterized by diminished muscle tone, feeding difficulties, and failure to grow and gain weight during infancy; short stature; genital abnormalities; and learning difficulties.
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angelman syndrome
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Developmental delay, functionally severe
Speech impairment, none or minimal use of words; receptive and non-verbal communication skills higher than verbal ones |
