Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
11 Cards in this Set
- Front
- Back
|
Where are most cytosolic proteins synthesized |
Free ribosomes |
|
|
Most secreted proteins are synthesized |
RER and Golgi |
|
|
Cotranslational transport |
proteins are transported across RER membrane during translation |
|
|
Post translational transport |
protein is synthesized in cytosol and then moved to ER |
|
|
N-Terminal targeting sequence |
Specifies final destination of protein is rER and binds to Signal Recognition Particle |
|
|
4 Features of a stably folded protein |
Hydrophobic side buried Charged sides on surface Cysteine-Cysteine disulfide bonds Minimal energy state |
|
|
Beta-bends |
allows changing of direction of the peptide chain to get a folded structure |
|
|
Amyloid |
Generic term describing misfolded protein aggregates |
|
|
Chaperones/Heat Shock Protein |
Assist in the correct folding of proteins and to prevent misfolded proteins from becoming a problem |
|
|
Chaperonins |
Barrel shaped proteins that create an internal environment that is favorable for correctly folding proteins |
|
|
Proteasomes |
Recognizes ubiquitin tagged proteins and destroys them |
