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11 Cards in this Set
- Front
- Back
differential regions (of sex chromosomes)
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where most of the genes are located, not many sex genes
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forward genetics
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the classical approach to genetic analysis, in which genes are first identified by mutant alleles and mutant phenotypes and later cloned and subjected to molecular analysis
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haplosufficiency
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describes a gene that, in a diploid cell, can promote wild type function in only one copy (dose)
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hemizygous gene
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a gene present in only one copy in a diploid organism-for example, an X-linked gene in a male mammal
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heterogametic sex
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the sex that has heteromorphic sex chromosomes (eg. XY) and hence produces two different kinds of gametes with respect to the sex chromosomes
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homogametic sex
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the sex with homologous sex chromosomes (eg. XX or YY)
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kinetochore
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a complex of proteins to which a nuclear spindle fiber attaches
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pseudoautosomal regions
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a region on a sex chromosome that is homologous to a region on the other heterogametic sex chromosome; they act as substrates for meiotic pairing and crossing over
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sex chromosomes
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a chromosome whose presence or absence is correlated with the sex of the bearer; a chromosome that plays a role in sex determination
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sex linkage
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the location of a gene on a sex chromosome
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SRY gene
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the maleness gene, residing on the Y chromosome
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