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11 Cards in this Set

  • Front
  • Back
differential regions (of sex chromosomes)
where most of the genes are located, not many sex genes
forward genetics
the classical approach to genetic analysis, in which genes are first identified by mutant alleles and mutant phenotypes and later cloned and subjected to molecular analysis
haplosufficiency
describes a gene that, in a diploid cell, can promote wild type function in only one copy (dose)
hemizygous gene
a gene present in only one copy in a diploid organism-for example, an X-linked gene in a male mammal
heterogametic sex
the sex that has heteromorphic sex chromosomes (eg. XY) and hence produces two different kinds of gametes with respect to the sex chromosomes
homogametic sex
the sex with homologous sex chromosomes (eg. XX or YY)
kinetochore
a complex of proteins to which a nuclear spindle fiber attaches
pseudoautosomal regions
a region on a sex chromosome that is homologous to a region on the other heterogametic sex chromosome; they act as substrates for meiotic pairing and crossing over
sex chromosomes
a chromosome whose presence or absence is correlated with the sex of the bearer; a chromosome that plays a role in sex determination
sex linkage
the location of a gene on a sex chromosome
SRY gene
the maleness gene, residing on the Y chromosome