Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
|
VITAMIN MALNUTRITION
|
VITAMIN MALNUTRITION
|
|
|
essential organic materials required as co-enzymes in metabolic process... water soluble are? fat soluble?
|
B,C
A,D,E,K |
|
|
Vitamin B, water soluble
B1-2-3-6-12 |
1-thiamine
2-riboflavin 3-niacin,nicotinic acid 6-pyridoxine 12-cyanocobalamin |
|
|
fxn of B1-thiamine?
|
thiamine pyrophosphate in liver- is coenzyme in carb metabolism
its deficiency(beriberi) impair energy production and ATP supply |
|
|
manifestation of deficiency:
Heart(wet beriberi)- assoc with peripheral vasodilation NE appearance is? |
flabby dilated heart
heart failure-peripherla edema |
|
|
CNS(dry beriberi)
Peripheral neuropathy presents? |
symmetrical motor/sensory
degeneration of myelin sheath, disrupt axon start in feet and legs--> extend prox numbness and tingling muscle tenderness/atrophy |
|
|
Brain(wernicle-korsakoff syndrome)
most in chronic ______ in the western world. |
alcoholics
|
|
|
wernicke-korsakoff syndrome leads to?
|
ataxia, confusion, loss equilibrium, dementia
|
|
|
B2 Riboflavin
FXN, constituents of? coenzyme which participates in a wide range of? |
flavoprotein
2. oxidation-reduction rxns -deficiency impairs energy production |
|
|
manifestations of deficiency include?
|
1.lips-cheilosis(first and most characteristic
2.tongue-glossitis 3.eye-conjuctivitis 4. skin- scaling dermatitis 5. bone marrow- normocytic, normochromic anemia |
|
|
B3- niacin, nicotinic acid
Fxn is integral part of co-enzymes involved in? |
oxidation-redox rxns
|
|
|
B3 deficiency causes pallegra (3D's)?
|
dermatitis
diarrhea dementia |
|
|
B6 pyridoxine
FXN is? manifestations are similar to other B vitamins. |
formation of pyridoxal phospahte, co-enzyme in protein metabolism
|
|
|
B12-cyanocobalamin
Fxn is? |
bind with intrinsic factor by parietal cells of stomach--- absorbed in ileum, stored in liver
|
|
|
Pernicious Anemia: autoimmune disease produces?
|
antibodies against parietal cells cauusing deficiency in intrinsic factor
|
|
|
Vitamin C-Ascorbic acid
Deficiency causes? Fxn: essential for conversion of proline into hydroxyproline of_____ |
1. scurvy
2.collagen |
|
|
manifestations of Vitamin C deficiency :
decreased tensile strength of? 2. increased capillary fragility leads to? 3. impaired______healing 4. anemia due to? |
1.collagen fibers
2. tendency to bleed in skin 3. wound healing, 4. impaired iron absorption and bl loss |
|
|
Manifestations cont:
5. skeletal changes of infants and children... 6. adults |
overgrowth of cartilage, bones yield due to weight bearing and muscle tension
6. decrease new bone formation, rarefaction of bones(less dense) |
|
|
Vitamin A retinol:
Fxns: precursor of light sensitive pigments 2. iodopsin in cones for? 1. rhodospin in rods for? |
1. night vision
2. daytime vision |
|
|
manifestations of deficiency for Vitamin A include?
|
visual impairment
hyperplasia and keratinization of stratified squam epithelium+ squamos metaplasia of glandular epithelium |
|
|
Vitamin D
Fxn is? |
stimulate parathyroid hormone
-calcium absorption -mobilization of calcium from the bone |
|
|
Vit D deficiency leads to ?
|
rickets in children- mineralization of bones- bowing of legs
-osteomalacia in adults |
|
|
Vitamin E
Fxn: Acts as a? protects against? |
1. antioxidant- neutralize free radicals
2. hemolysis of RBC's, retrolental fibrosis in premature babies receiving oxygen |
|
|
manifestation of deficiency :
degeneration of axon and? |
myelin in posterior column of SP cord
|
|
|
Vitamin K
Fxn- synthesis of ? |
coagulation factors in liver
2,7,9,10 |
|
|
cause of Vitamin K deficiency:
intestinal malabsorption of? 2. vitamin K antagonist? |
fat
2. coumadin 3, liver disease |
|
|
manifestation of deficiency leads to?
|
prolonged coagulation time
and bleeding tendency |
