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20 Cards in this Set
- Front
- Back
neutrophil:
appearance granular? % function |
-lobulated nucleus. larger than RBC
-yes - 60-65% -first response. Phagocytosis |
|
eosinophil:
granular? appearance % function |
-yes
-reddish-orange granules. size>RBC - 1-2% - allergic rxn's, parasites |
|
basophil:
granular? appearance % function |
-yes
- size>RBC. Prominent bluish-purple granules - <1% - |
|
lymphocyte:
granular? appearance % function |
- no
- size = RBC. Large dark blue nucleus - 30-35% - |
|
monocyte:
granular? appearance % function |
- no
- large! Pale, horseshoe-shaped nucleus. Lots of cytoplasm. - 2-5% - |
|
leukocytosis vs. leukemia
|
leukocytosis: increase in WBCs
leukemia: increase in blast type cells |
|
decrease in WBCs
|
-leukopenia
|
|
neutrophilic leukocytosis:
indicates |
-pyogenic bacterial infection
-(and shift to left?) |
|
lymphocytic leukocytosis:
indicates |
-viral infection
|
|
eosinophilic leukocytosis:
indicates |
-parasitic infection
-allergic rxn |
|
in tissue:
basophils B lymphocytes monocytes (5) |
-mast cell relatives (?)
-plasma cells -histiocyte, macrophage -multinucleated giant cell (response to foreign body) -Langhans type giant cell (tuberculosis) -foam cell histiocytes |
|
cell composition of infection:
acute chronic subacute |
-neutrophils
-lymphocytes, plasma cells, macrophages -mix of all of the above |
|
what kind of inflammation is mainly histiocytes and multinucleated giant cells?
|
-chronic granulomatous inflammation
|
|
how does appearance of neutrophil change in tissue?
Does name change? |
-loses cytoplasmic granularity. (retains lobed nucleus)
-no |
|
at what stage do lymphocytes migrate into tissue?
appearance? name? |
-later healing stage
-single small round dark nucleus. No visible cytoplasm -same (lymphocyte) |
|
plasma cell:
origin appearance |
- B-cells
- oval, off-center nucleus - sometimes reddish-brown cytoplasm |
|
Macrophage/histiocyte:
origin migrates in response to appearance |
-monocyte
-bacterial, viral, fungal infections. Indicative of chronic infection. -large, pale nucleus. Sometimes has 1 small round dark centric nucleolus |
|
foam cell type:
origin appearance cause |
-histiocyte (monocyte)
-dark nucleus, foamy cytoplasm -happens when histiocytes/macrophages phagocytize material |
|
hemocerin
|
-iron containing pigment
-macrophages eat (if you are bleeding) and turn brown |
|
multinucleated giant cells:
2 types |
Foreign body type:
-random distribution of nuclei Langhan's type: -nuclei form horseshoe shape around periphery -response to mycobacterium tuberculosis, a few fungal infections -causes granulomatous inflammation |