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20 Cards in this Set

  • Front
  • Back
neutrophil:
appearance
granular?
%
function
-lobulated nucleus. larger than RBC
-yes
- 60-65%
-first response. Phagocytosis
eosinophil:
granular?
appearance
%
function
-yes
-reddish-orange granules. size>RBC
- 1-2%
- allergic rxn's, parasites
basophil:
granular?
appearance
%
function
-yes
- size>RBC. Prominent bluish-purple granules
- <1%
-
lymphocyte:
granular?
appearance
%
function
- no
- size = RBC. Large dark blue nucleus
- 30-35%
-
monocyte:
granular?
appearance
%
function
- no
- large! Pale, horseshoe-shaped nucleus. Lots of cytoplasm.
- 2-5%
-
leukocytosis vs. leukemia
leukocytosis: increase in WBCs

leukemia: increase in blast type cells
decrease in WBCs
-leukopenia
neutrophilic leukocytosis:
indicates
-pyogenic bacterial infection
-(and shift to left?)
lymphocytic leukocytosis:
indicates
-viral infection
eosinophilic leukocytosis:
indicates
-parasitic infection
-allergic rxn
in tissue:
basophils
B lymphocytes
monocytes (5)
-mast cell relatives (?)
-plasma cells

-histiocyte, macrophage
-multinucleated giant cell (response to foreign body)
-Langhans type giant cell (tuberculosis)
-foam cell histiocytes
cell composition of infection:
acute
chronic
subacute
-neutrophils

-lymphocytes, plasma cells, macrophages

-mix of all of the above
what kind of inflammation is mainly histiocytes and multinucleated giant cells?
-chronic granulomatous inflammation
how does appearance of neutrophil change in tissue?
Does name change?
-loses cytoplasmic granularity. (retains lobed nucleus)

-no
at what stage do lymphocytes migrate into tissue?
appearance?
name?
-later healing stage
-single small round dark nucleus. No visible cytoplasm
-same (lymphocyte)
plasma cell:
origin
appearance
- B-cells
- oval, off-center nucleus
- sometimes reddish-brown cytoplasm
Macrophage/histiocyte:
origin
migrates in response to
appearance
-monocyte
-bacterial, viral, fungal infections. Indicative of chronic infection.
-large, pale nucleus. Sometimes has 1 small round dark centric nucleolus
foam cell type:
origin
appearance
cause
-histiocyte (monocyte)
-dark nucleus, foamy cytoplasm
-happens when histiocytes/macrophages phagocytize material
hemocerin
-iron containing pigment
-macrophages eat (if you are bleeding) and turn brown
multinucleated giant cells:
2 types
Foreign body type:
-random distribution of nuclei

Langhan's type:
-nuclei form horseshoe shape around periphery
-response to mycobacterium tuberculosis, a few fungal infections
-causes granulomatous inflammation