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64 Cards in this Set
- Front
- Back
Most sensitive and specific marker for MI |
Trop I, Trop T |
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Most common cause of sudden cardiac death |
CAD |
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Most common mechanism of sudden cardiac death |
Lethal arrhythmia (asystole or vfib) |
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Most common cause of MVP |
Unknown Fibrillin-1 gene defect |
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Most commonly involved valve in RHD |
Mitral valve |
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Hallmark of infective endocarditis |
Vegetations |
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Most commonly affected valves in infective endocarditis |
Aortic and mitral valves Right valves in IV drug users |
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Most common cause of myocarditis |
Viral (Coxsackie A, B, enteroviruses) |
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Most common primary cardiac tumor in adults |
Myxoma |
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Most common primary cardiac tumor in children |
Rhabdomyoma |
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Most common acute pericarditis |
Fibrinous/serofibrinous |
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Most common hemorrhagic cause of acute pericarditis |
Neoplasms |
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Most striking clinical finding in acute pericarditis |
Pericardial friction rub |
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Most common cause of agranulocytosis |
Drug toxicity |
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3 characteristic morphologies of lymphadenitis |
Follicular hyperplasia Paracortical hyperplasia Sinus histiocytosis |
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Histologic finding in ALL |
Hypercellular marrow with lymphoblasts |
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Auer rods |
Needle-like azurophilic granules |
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Faggot cells |
Cells with numerous Auer rods |
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Most common leukemia of adults in Western world |
CLL |
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Histologic findings in CLL |
LN: effaced architecture, small lymphocytes with proliferation cenfers PBS: small lymphocytes with smudge cells |
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Reed Sternberg cells |
Large, multiple nuclei or single with multiple lobes Seen in Hodgkin Lymphoma |
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5 subtypes of Hodgkin Lymphoma |
Nodular sclerosis Mixed cellularity Lymphocyte rich Lymphocyte depleted Lymphocyte predominant |
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Most common form of NHL |
Diffuse Large B cell Lymphoma |
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Most common lymphoma of adults |
Diffuse Large B cell Lymphoma |
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Most common indolent lymphoma of adults |
Follicular lymphomq |
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Most common Hodgkin Lymphoma |
Nodular sclerosis |
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4 types of NHL B cell lymphoma |
Follicular lymphoma Difffuse large B cell lymphoma Burkitt lymphoma Marginal zone lymphoma |
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Most important plasma cell neoplasm |
Multiple myeloma |
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Histologic finding in Burkitt Lymphoma |
Starry sky pattern -diffuse infiltration of medium-sized anaplastic lymphocytes (sky) -punctuated with macrophages that phagocytose apoptotic lymphocytes (star) |
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Most common causes of death in multiple myeloma |
Infection Renal failure |
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Histologic findings in multiple myeloma |
Lymphocytes, plasma cells, plasmacytoid lymphocytes with mast hyperplasia PAS (+) cytoplasmic/nuclear inclusion containing Ig -- Russel/Dutcher bodies |
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Chronic myeloproliferative disorders due to JAK2 mutation |
Polycythemia vera Essential thrombocytosis Primary myelofibrosis |
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Most common type of thymoma |
SCC |
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Most common cause of hyperpituitarism |
Functional anterior pituitary adenoma |
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Most common anterior pituitary adenoma |
Prolactin cell adenoma |
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Nelson syndrome |
Development of large, destructive pituitary adenoma post-adrenelectomy for tx of Cushing syndrome |
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Sequence of hormonal function loss |
GH, FSH, LH --> TSH, ACTH --> PRL |
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Most common skeletal dysplasia |
Achondroplasia |
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Most common lethal form of dwarfism |
Thanatophoric dwarfism |
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Most common arrhythmia in hyperthyroidism |
Afib |
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Most common arrhythmia in hyperthyroidism |
Afib |
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Most common cause of congenital hypothyroidism worldwide |
Iodine deficiency |
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Most common cause of hypothyroidism in iodine-sufficient areas |
Hashimoto's disease |
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Most common thyroid anomaly |
Thyroglossal duct cyst |
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Most common cause of endogenous hyperthyroidism |
Graves disease |
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Difference between Plummer Syndrome and Graves Disease |
MNG appearance No ophthalmopathy and dermopathy |
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Most common inherited disorder of connective tissue |
Osteogenesis imperfecta |
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Most common cause of secondary hyperparathyroidism |
Renal failure |
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Most common cause of primary hyperthyroidism |
Adenoma |
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Most common of the intraosseous cartilage tumor |
Chondroma |
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Most common primary optic nerve tumor |
Pilocytic astrocytoma Meningioma |
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Most important cause of optic neuritis |
Multiple sclerosis |
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Most common type of retinal lymphoma |
Diffuse Large B cell lymphoma |
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Most common primary intraocular malignancy in children |
Retinoblastoma |
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Most common intraocular malignancy |
Metastasis to uvea |
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Most common primary intraocular malignancy in adults |
Melanoma |
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Most common first evidence of metastases of uveal melanoma |
Liver |
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Most common poorly differentiated tumor |
Medulloblastoma |
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Most common CNS neoplasm in immunocompromised individuals |
Primary CNS lymphoma |
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Most common origin of primary CNS lymphoma |
B cell lymphoma |
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Most common subtype of primary CNS lymphoma |
Diffuse Large B cell lymphoma |
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Most common site of conjunctival neoplasm |
Limbus |
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Most common malignancy of the eyelid |
Basal cell carcinoma |
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Most common demyelinating disorder |
Multiple sclerosis |