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64 Cards in this Set

  • Front
  • Back

Most sensitive and specific marker for MI

Trop I, Trop T

Most common cause of sudden cardiac death

CAD

Most common mechanism of sudden cardiac death

Lethal arrhythmia (asystole or vfib)

Most common cause of MVP

Unknown


Fibrillin-1 gene defect

Most commonly involved valve in RHD

Mitral valve

Hallmark of infective endocarditis

Vegetations

Most commonly affected valves in infective endocarditis

Aortic and mitral valves


Right valves in IV drug users

Most common cause of myocarditis

Viral (Coxsackie A, B, enteroviruses)

Most common primary cardiac tumor in adults

Myxoma

Most common primary cardiac tumor in children

Rhabdomyoma

Most common acute pericarditis

Fibrinous/serofibrinous

Most common hemorrhagic cause of acute pericarditis

Neoplasms

Most striking clinical finding in acute pericarditis

Pericardial friction rub

Most common cause of agranulocytosis

Drug toxicity

3 characteristic morphologies of lymphadenitis

Follicular hyperplasia


Paracortical hyperplasia


Sinus histiocytosis

Histologic finding in ALL

Hypercellular marrow with lymphoblasts

Auer rods

Needle-like azurophilic granules

Faggot cells

Cells with numerous Auer rods

Most common leukemia of adults in Western world

CLL

Histologic findings in CLL

LN: effaced architecture, small lymphocytes with proliferation cenfers


PBS: small lymphocytes with smudge cells

Reed Sternberg cells

Large, multiple nuclei or single with multiple lobes


Seen in Hodgkin Lymphoma

5 subtypes of Hodgkin Lymphoma

Nodular sclerosis


Mixed cellularity


Lymphocyte rich


Lymphocyte depleted


Lymphocyte predominant

Most common form of NHL

Diffuse Large B cell Lymphoma

Most common lymphoma of adults

Diffuse Large B cell Lymphoma

Most common indolent lymphoma of adults

Follicular lymphomq

Most common Hodgkin Lymphoma

Nodular sclerosis

4 types of NHL B cell lymphoma

Follicular lymphoma


Difffuse large B cell lymphoma


Burkitt lymphoma


Marginal zone lymphoma

Most important plasma cell neoplasm

Multiple myeloma

Histologic finding in Burkitt Lymphoma

Starry sky pattern


-diffuse infiltration of medium-sized anaplastic lymphocytes (sky)


-punctuated with macrophages that phagocytose apoptotic lymphocytes (star)

Most common causes of death in multiple myeloma

Infection


Renal failure

Histologic findings in multiple myeloma

Lymphocytes, plasma cells, plasmacytoid lymphocytes with mast hyperplasia


PAS (+) cytoplasmic/nuclear inclusion containing Ig -- Russel/Dutcher bodies

Chronic myeloproliferative disorders due to JAK2 mutation

Polycythemia vera


Essential thrombocytosis


Primary myelofibrosis

Most common type of thymoma

SCC

Most common cause of hyperpituitarism

Functional anterior pituitary adenoma

Most common anterior pituitary adenoma

Prolactin cell adenoma

Nelson syndrome

Development of large, destructive pituitary adenoma post-adrenelectomy for tx of Cushing syndrome

Sequence of hormonal function loss

GH, FSH, LH --> TSH, ACTH --> PRL

Most common skeletal dysplasia

Achondroplasia

Most common lethal form of dwarfism

Thanatophoric dwarfism

Most common arrhythmia in hyperthyroidism

Afib

Most common arrhythmia in hyperthyroidism

Afib

Most common cause of congenital hypothyroidism worldwide

Iodine deficiency

Most common cause of hypothyroidism in iodine-sufficient areas

Hashimoto's disease

Most common thyroid anomaly

Thyroglossal duct cyst

Most common cause of endogenous hyperthyroidism

Graves disease

Difference between Plummer Syndrome and Graves Disease

MNG appearance


No ophthalmopathy and dermopathy

Most common inherited disorder of connective tissue

Osteogenesis imperfecta

Most common cause of secondary hyperparathyroidism

Renal failure

Most common cause of primary hyperthyroidism

Adenoma

Most common of the intraosseous cartilage tumor

Chondroma

Most common primary optic nerve tumor

Pilocytic astrocytoma


Meningioma

Most important cause of optic neuritis

Multiple sclerosis

Most common type of retinal lymphoma

Diffuse Large B cell lymphoma

Most common primary intraocular malignancy in children

Retinoblastoma

Most common intraocular malignancy

Metastasis to uvea

Most common primary intraocular malignancy in adults

Melanoma

Most common first evidence of metastases of uveal melanoma

Liver

Most common poorly differentiated tumor

Medulloblastoma

Most common CNS neoplasm in immunocompromised individuals

Primary CNS lymphoma

Most common origin of primary CNS lymphoma

B cell lymphoma

Most common subtype of primary CNS lymphoma

Diffuse Large B cell lymphoma

Most common site of conjunctival neoplasm

Limbus

Most common malignancy of the eyelid

Basal cell carcinoma

Most common demyelinating disorder

Multiple sclerosis