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10 Cards in this Set

  • Front
  • Back
Antacids
calcium carbonate
magnesium hydroxide
aluminum hydroxide
differentiate magnesium and aluminum hydroxide
magnesium - laxative effect
aluminum - constipation
mechanism of axn of omeprazole/lansoprazole
irreversible blockade of H/K ATPase in active gastric parietal cells
possible chronic effects of proton pump inhibitors
hypergastrinemia
reduced bioavailability of Vit. B12 and other drugs that require acidity for gastrointestinal absorption
H2 blockers
Cimetidine
Famotidine
Ramitidine
toxicities of H2 blockers
CYP450 inhibitors
may reduce hepatic blood flow
Misoprostol
analog of PGE1 to increase mucosal protection and inhibit acid secretion
Sucralfate
aluminum sucrose sulfate that binds to injured to tissue and forms a protective coating over ulcer beds
two anticholinergic drugs (selectively M1) used in treatment of PUD
pirenzepine
telenzepine
activation of this receptor stimulates acid secretion by parietal cells
H2 receptor - via histamine