G Protein Linked 2Nd Messengers

Front 1

V2

Back 1

↑ H2O permeability and reabsorption in the collecting tubules of the kidney (Gs)

Front 2

V1

Back 2

↑ vascular smooth muscle contraction (Gq)

Front 3

H2

Back 3

↑ gastric secretion (Gs)

Front 4

D2

Back 4

modulates transmitter release, especially in the brain (Gi)

Front 5

M2

Back 5

↓ heart rate & contractility of atria (Gi)

Front 6

α2

Back 6

↓ sympathetic outflow, ↓ insuline release (Gi)

Front 7

M3

Back 7

↑ gut peristalsis, ↑ exocrine gland secretions (sweat/gastric), ↑ bladder contraction, bronchoconstriction, ↑ pupillary sphincter m. contraction (miosis), ciliary m. contraction (accommodation) (Gq)

Front 8

β1

Back 8

↑ heart rate, ↑ contractility, ↑ renin release, ↑ lipolisis (Gs)

Front 9

β2

Back 9

↑ contractility, ↑ HR, vasodilation, bronchodilation, ↑ lipolisis, ↑ insulin release, ↓ uterine tone (Gs)

Front 10

α2

Back 10

↓ sympathetic outflow, ↓ insulin release (Gi)

Front 11

D1

Back 11

relaxes renal vascular smooth muscle (Gs)

Front 12

H1

Back 12

↑ nasal & bronchial mucus production, contraction of bronchioles, pruritis, & pain (Gq)

Front 13

M1

Back 13

CNS, enteric nervous system (Gq)

Front 14

α2

Back 14

↓ sympathetic outflow & ↓ insulin release (Gi)

Front 15

H1, α1, V1, M1, M3

Back 15

Gq (HAV 1 M & M)

Front 16

M2, α2, D2

Back 16

Gi (mad 2's)

Front 17

β1, β2, D1, H2, V2

Back 17

Gs

Front 18

Sympathetic G protein receptors

Back 18

α1 (q), α2 (i), β1(s), β2(s)

Front 19

Parasympathetic G protein receptors

Back 19

M1(q), M2(i), M3(q)

Front 20

Dopamine G protein receptors

Back 20

D1 (s), D2 (i)

Front 21

Histamine G protein receptors

Back 21

H1 (q), H2 (s)

Front 22

Vasopressin G protein receptors

Back 22

V1 (q) , V2 (s)

Front 23

Gq class stimulates....

Back 23

phospholipase C

Front 24

Gs.....

Back 24

stimulates adenylyl cyclase

Front 25

Gi

Back 25

inhibits adenylyl cyclase