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19 Cards in this Set
- Front
- Back
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Endophenotype is...
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~associated with illness
~heritable ~primarily state inependent (is present whether or not the disease is present) ~found in affected and unaffected family members more than the general population |
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Classic Working Memory defn.
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Central Executive and 2 slave systems;
visuospatial sketch pad->central executive->phonological loop (subvocal repetition) |
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Cowen defn. of Working Memory
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Subset of long-term memories that are currently active and the focus of attention; part of long term memories being used
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Ericsson & Kintsch defn. of Working Memory
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Concept of long-term working memory; skilled use of stored information
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We can store information in chunks of...
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7 elements (plus or minus two)
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Example of a working memory task
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Digit Span
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Selective Breeding
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start with outbred rats and mate high-high, low-low for phenotype of interest until you finally have 2 inbred strains
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Animal Model of Anxiety
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Elevated plus maze
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Animal Model of Depression
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Forced Swim Task
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Random Mutagenesis
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exposed thousands of male mice to a chemical mutagen and mate them with unaffected females
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Knock In/Out Model
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Take the gene of interest and either introduce (in) or remove (out) the gene of interest
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BMI equation
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weight in kg.
------------------ height in m^2 |
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Underweight BMI
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18.5
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Overweight BMI
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25.0
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Obese BMI
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30.0
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Gene involved with Obesity
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Leptin gene
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2 Features of Anorexia Nervosa
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~Fear of gaining weight
~Body Disturbance |
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2 Features of Bulimia Nervosa
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~Binge Eating
~Lack of Control over eating |
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Candidate Genes Associated with Eating Disorders
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SLC6A4 (BN)
BDNF (AN) |
