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24 Cards in this Set

  • Front
  • Back
ADHD Inattention Symptom
Easily distracted
ADHD Hyperactivity Symptom
Difficulty playing quietly
ADHD Impulsivity Symptom
Difficulty awaiting turn
Familial influences on ADHD
~Males are more likely
~Prenatal exposure to cigarette smoke
~Heritability of 60-90%
Genes for ADHD
~DAT1
~DRD4
Dopamine Hypothesis
reduced dopamine circulation in those with attention problems and excessive dopamine in those with hyperactivity; hyperactives constantly seek out activities that boost dopamine levels
Psychosocial Adversity Index
the type of environment you grow up in affects your risk of developing ADHD
Pre-natal exposure to nicotine...
has a humongous effect on the risk of developing ADHD
Broad Domains of Autistic Disorders
~qualitative impairment in social interaction
~qualitative impairments in communication
~restricted repetitive and stereotyped patterns
Example of Impairment in Social Interaction (Autism)
Failure to develop peer relationships
Example of Impairments in Communication
Delay in, or total lack of, the development of spoken language
Example of Repetitive and Stereotyped Patterns
Persistent preoccupation with parts of objects
Vaccines and Autism
no longer considered a risk factor
Two Extremely Significant Factors in Autism Risk
Smoking during pregnancy
Birth Order
Candidate Genes for Autism
SLC6A4
A cellular marker of aging
Shortening of the telomeres that protect the ends of chromosomes
Environmental Factors on Telomere Shortening
~Dietary Restriction
~Obesity
~Smoking
~Exercise
~Stress
Why C.elegans is a great model
~short life cycle
~easy to study
~Small amount of DNA that can be developmentally traced
Dauer Stage
~A stage started by heat, crowding, and food shortage.
~Can live up to 3 months
~Mutation responsible for extending life span in the presence of food restriction
Genes Involved in Human Longevity
~Sirutin
~TOR kinase
~Insulin/IGF-1 pathway
Exercise and activity is shown to...
increase quality of life
Alzheimer's is Caused by...
Amyloid Plaques and Tangles
Rare Type Alzheimer's
~early-onset
~affects 1/10,000
~Gene involved is PS1 and PS2
~Autosomal dominant
Common Type Alzheimer's
~onset 70+ years
~APOE4
~Complex Disorder