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13 Cards in this Set
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Histoplasma
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"50-85% asymp. Acute pneumonic syndrome most freq. Dry cough, erythema nodosum. Self-limited, last several wks. Thoracic syndromes: chronic histoplasmosis: Fatigue, wt loss, chronic cough. Pericarditis: rxn to adjacent infected mediastinal lymph nodes. Fibrosing mediastinitis: may obstruc vena cava & others, excessive caseation or lymph nodes & fibrosis. Disseminated histo: in depressed CMI (AIDS), wt loss, HSmegaly, pancytopenia, painful oral ulcers, Addison's disease (from involvement of adrenals), meningitis, EN can also occur here."
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Blastomyces
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"Present as pneumonia, but can disseminate: verrucous or ulcerating masses. Involve bones and joints. Meningitis less common."
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Sporothrix
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"Erythematous lesion at trauma site->(MAY) enlarge, painless nodue-> nodules, pustules, ulcers along lymph drainage. Ocassionally: pneumo, bone, joint infec. "
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Paracoccidioides
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"Ulcerating skin, nasal and oral lesions in men w/ alcohol & tobacco habit, LyAd"
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Penicillium
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"Disseminated infec w/ fever, wt loss, papular skin lesions, HSmegaly, lymphadenopathy (LyAd). "
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Coccidioides
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"Sypms w/ increasing age (>60yrs). 60% asymp, but POS skin test. Pulmonary syndrome: blood eos, hilar or mediastinal adenopathy, night sweats(profuse), fatigue, wt loss, headache. Rashes: erythema multiforme (target lesions, necklace-looking), erythema nodosum (violaceous & painful). Dissemination: skin, bone, joint, meninges(fatal if untreated)->hydrocephalus"
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Aspergillus
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"ABPA: Pulmo infiltrates and marked Eosinophilia and IgE/IgE. Aspergilloma: fungus ball, mass of mycelia, mucus, tissue debris. Hemoptysis. Chronic necrotizing: Fever, cough, wt loss over mths. IPA: X-ray-""halo"" and ""air-crescent"" signs, and nodular infiltrates. "
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Cryptococcus
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"Pneumonia. Disseminated: meningitis, subQ nodules. "
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Fusarium
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"Fusarium keratitis: redness, pain, tearing and discharge from eye. Other lesions in bone, joints, and nail bed. Fever is common. Immunocompromised: disseminated, multiorgan."
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Mucor & Rhizopus
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Pt w/ diabetic ketoacidosis, burns, or leukemia are susceptible.
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Candida
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"Cutaneous candidiasis: paronychium-. There is redness and purulence along body fold. Intertrigo- Inflammation in body folds, eryth, pruritic, oozing lesions, penis and scrotum may be involved. Oral candidiasis: Angular cheilitis- fissures at the corner of mouth. Eryth candidiasis- eryth patches on the palate w/ mid-line loss pf papilliation on tongue, burning of mouth when eating. Pseudomembrane candidiasis- patches of eryth, can be removed by tongue blade, can be on tongue, cheeks, uvula and posterior pharynx. Vaginal candidiasis: pruritis, thick white discharge, erythema and pseudomembrane. "
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Candida
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"Esophageal candidiasis: dysphagia and odynophagia(painful swallow). Chronic mucocutaneous candidiasis: progressively worsening, superficial candidiasis and endocrinopathies. Fungemia: fever, tachycardia, mimics sepsis. Endopthalmitis, skin lesions, muscle abscesses. "
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Pneumocystis
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"Progressive dyspnea over wks, fever, dry cough. "
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