Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
17 Cards in this Set
- Front
- Back
|
Antifungal drug class that targets Membrane function
|
Polyenes - by binding ergosterol and destabilizing the membrane
|
|
|
Antifungal drug class that targets Cell wall synthesis
|
Echinocandins
|
|
|
Antifungal drug class that targets nucleic acid synthesis
|
5-Flu
|
|
|
Antifungal drug class that targets Ergosterol biosynthesis
|
Azoles - at Erg 11. At other locations: Lamisil, Tinactin
|
|
|
Dimorphic fungi - 5 types
|
Sporotrix, Blastomyces, Coccidioides, Histoplasma, Penicillium. Cause damage to cooler skin of extremities
|
|
|
Sporotrix,
|
Must be implanted into the skin to cause disease - "trix sticks into your skin"
|
|
|
Blastomyces,
|
Associated with swamps, inhaled. Causes severe destruction of skin and mucosa.
|
|
|
Coccidioides,
|
"California coccidioides." Inhaled. Mucosal and cutaneous infection.
|
|
|
Histoplasma,
|
Inhaled spores. Can be latent and shows up with suppression "plasma - asthma (respiratiory)". Midwest US. infects skin. AIDS.
|
|
|
Penniciluim
|
Inhaled. Asian AIDS patients.
|
|
|
5 opportunistic fungi diseases
|
Aspergillosis
Aspergillus spp. Cryptococcosis Cryptococcus neoformans Rare Candidiasis Candida albicans and related species. Common Zygomycosis (Mucormycosis) Rhizopus, Mucor, Rhizomucor, Absidia etc. Rare Pc Pneumonia Pneumocystis carinhi |
|
|
Aspergillus
|
Found in soil "asparagus - aspergillus" Causes pulmonary infection and necrosis in IC patients. Causes fungal sinusitis in IC patients
|
|
|
Cryptococcus
|
Vancouver island mystery - "cryptic" - Cutaneous and skin lesions
|
|
|
Mycormycosis/Zygomycosis
|
Skin, sinus, blood vessel colonization by a variety of species - Rhizo- Mucor-
|
|
|
Pc Pneumonia
|
Cused by pneumocystis carinii. Commensal infection in non-IC people. common cause of AIDS death.
|
|
|
Fusarium
|
contaminated contact lens solution
|
|
|
stachybotrys
|
black mold; irritant, not fatal
|
