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17 Cards in this Set
- Front
- Back
Histoplasmosis
|
Histoplasma capsulatum
Soils in MidWest US Central and South America Ohio Valley Fever Primary |
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Blastomycosis
|
Blastomyces dermatitidis
Soils Appalachia Gilchirst or Chigaco disease Primary |
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Coccidioidomycosis
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Coccidioides immitis
Soils SW - Texas Valley Fever Primary |
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Paracoccidioidomycosis
|
Paracoccidioides brasiliensis
Soils in South America - most rare of primary Primary |
|
Sporotrichosis
|
Sporothrix schenckii
Soil Rose Gardners disease Intermediate |
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Dermatophytosis (ringworms and tinea)
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Microsporum, Trichophyton, Epidermophyton
Skin and hair Ringworm Intermediate |
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Candidiasis
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Candida albicans
Mouth, throat, vagina thrush Secondary opportunistic |
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Apergillosis
|
Aspergillus
Soil, airborne, very pervsassive Secondary opportunistic Mycotoxicosis - aflatoxin |
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Cryptococcosis
|
Cryptococcus Neoformans
Pigeon roosts Secondary opportunistic |
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Mucormycosis
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Thizopus, absidia, Mucor
Soil, dust and human habitation Secondary opportunistic |
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Zygomycota
|
opportunistic
|
|
Antifungal drugs
|
Polyenes, Azoles, Allylamines
|
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Polyene
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Disrupt plasma membrane and cause leakage in cytoplasm
Amphotericin B Nystatin |
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Azoles
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Interfere with ergosterol synthesis, lead to defective cell membrane
Imidazoles Triazoles |
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Allylamines
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Inhibit an enzyme in ergosterol synthesis
Naftifine Lamisil |
|
Ecinocandins
|
Block polysaccharide synthesis
Caspofungin |
|
Cell division
Nucleic Acid synthesis |
Griseofulvin
Flucytosine |