Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Host factors that contribute to resistance against fungal infections
|
pH, fatty acid content of skin, epithelial turnover and normal bacterial flora
|
|
|
Coccidioides immitis
|
Fungi that can cause coccidioides meningitis
result of inhaling soil or dust dimorphic physiology (yeast in humans, mold in nature) Most infections are subcliical in CA known as valley fever. 40% develop pneumonia Diagnosis by history, positive skin test, serum antibody to C. immitis, positive culture from an extraneural site and exclusion of other etiologies for chronic meningitis |
|
|
Cryptococcus neoformans
|
Fungi that causes cryptococcosis
It looks like a yeast expresses a polysaccharide capsule during human infection that inhibits phagocytosis. looks like yeast-not dimorphic Acquired through inhalation of avian droppings, especially from pigeons. May survive up to two years in dust. |
|
|
Modes of parasitic Entry:
|
Ingestion
Direct penetration by arthropod bite Transplacental penetration Organism directed penetration |
|
|
Primary Amoebic Meningoencephalitis (PAM)
|
Caused by a protozoan, Naegleria fowleri, an amoeboflagellate found in fresh water, especially stagnant water
A disease of healthy young people acquired by swimming Pathogenesis- Organism enters through nares, through nasal mucosa covering cribiform plate Migrates to CNS and multiplies with extensive damage to the meninges, and olfactory bulbs, and extends in large numbers via the perivascular spaces into the brain Causes acute inflammatory response in the meninges, with PMN in large numbers, and elevated protein and low to normal glucose in the CSF |
|
|
Cysticercosis
|
Caused by infection with eggs of Taenia solium, the pork tapeworm. However cysticercosis is initiated by infection of a human by another infected human.
Endemic in: Mexico, South America, China, India Eggs develops, the larva penetrates the gut wall and can go almost anywhere in the body and develop into cysticerci, especially in muscle. Most common clinical problem is neurocysticercosis, with cysticerci found within the cerebrum, in the subarachnoid space, or in the ventricles |
|
|
Infection with cystercercus
|
Cysticercus in mm of pig human ingests it raw in pork. Infection occurs. Larva hatch in small intestine and grow to become adults. Head of adult attaches to wall of small intestine and GRAVID PROGLOTTID is released. GRAVID PROGLOTTID is an egg producing organ. We are now at the diagnostic stage where eggs or GRAVID PROGLOTTID can be found in feces or environment.
|
|
|
Formation of Cistercercosis
|
Embronated egg or proglottid is ingested hatches and penetrates the intestinal wall and enter into the bloodstream. Larva make it to mm, CT, brain, lungs, eyes, cacify to form a Cistercercosis
|
|
|
Diagnosis of Cistercercosis
|
look for space occupying lesions, Serology
Cysticerci remain viable 3-5 years and then degenerates Need to screen for contacts of cases who are carriers and treat so others are not infected (carrier have eggs present in their feces) |
