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37 Cards in this Set

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Advil (ibuprofen) - 400 mg q 4-6 hours PRN pain
Class: Nonopioid Analgesic, antipyretic, antirheumatics, NSAIDs
Indications: mild-moderate pain, inflammation, lowering fever
Action: inhibits prostiglandin synthesis
Therapeutic Effects: decreased pain & inflammation,reduction of fever
Safe Dosage:
200-400 mg q 4-6 hrs ( X exceed 1,200 mg/day)
Medication Interactions:
Additive adverse GI side effects with aspirin, oral potassium and other NSAIDs, corticosteroids, or alcohol
Chronic use with acetaminophen may ↑ risk of adverse renal reactions
May ↓ effectivenessof diuretics or antihypertensives
May ↑ hypoglycemic effects of insulin or oral hypoglycemic agents
May slightly ↑ serum digoxin levels
↑ risk of bleeding with drugs effecting platelet function
Advil
Side Effects:
CNS: headache, dizziness, drowsiness, psychic disturbances
EENT: amblyopia, blurred vision, tinnitus
CV: arrhythmias, edema
GI: GI BLEEDING, HEPATITIS, constipation, dyspepsia, nausea, vomiting, abdominal discomfort
GU: cystitis, hematuria, renal failure
Derm: EXFOLIATIVE DERMATITIS, STEVENS-JOHNSONSYNDROME, TOXIC EPIDERMAL NECROLYSIS, rashes
Hemat: blood dyscrasias, prolonged bleeding time
Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS
Nursing Considerations:
Geri: ↑ risk for GI bleeding. ↑ risk of hepatic & renal toxicity. Assess for s/s symptoms of GI bleeding, renal dysfunction, & hepatic impairment
Use ↓ effective dose for shortest time
Coadmin w/ opioid analgesics may have + analgesic effects & may permit ↓ opioid doses
Pain: Assess pain prior to & 1–2 hr after
PO: For rapid initial effect, admin 30 min before or 2 hr after meals. May be admin w/ food, milk, or antacids. Tabs may be put in fluids or food. Take w/ a full glass of water & remain in upright position for 15–30 min after admin
Amoxicillin 500 mg BID x 3 weeks PO
Class: aminopenicillins
Indications: Treats skin & skin structure infections, Otitis media, Sinusitis, Resp & GU infections.
Action: Binds to bacterial cell wall, causing cell death
Safe Dosage: 500–875 mg q 12 hr (not to exceed 2–3 g/day)
May be given w/o regard to meals or w/ meals to - GI side effects. Capsule contents may be emptied & swallowed with liquids
Med Interactions: none on this list
Side Effects:
CNS: SEIZURES (HIGH DOSES)
GI: PSEUDOMEMBRANOUS COLITIS, diarrhea, nausea, vomiting, ↑ liver enzymes
Derm: rash, urticaria
Hemat: blood dyscrasias
Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS, SERUM SICKNESS, superinfection
Nursing Considerations:
use cautiously in severe renal insufficiency, Infectious mononucleosis, acute lymphocytic leukemia, or cytomegalovirus infection
Amoxicillin
Nursing Considerations:
tell patient finish drug completely. sharing med is dangerous.
Assess for infection at beginning & throughout. Obtain a history before initiating therapy to determine previous use of & reactions to penicillins or cephalosporins.
Observe for s/s of anaphylaxis (rash, pruritus, laryngeal edema, wheezing). Notify PCP immediately if these occur.
Obtain specimens for culture and sensitivity prior to therapy. First dose may be given before receiving results.
Monitor bowel function. Diarrhea, abdominal cramping, fever, and bloody stools should be reported to health care professional promptly as a sign of pseudomembranous colitis. May begin up to several weeks following cessation of therapy.
Cardizem 180 mg QD
Class: Calcium Channel Blocker, antianginal, antihypertensives
Indications: Hypertension, Angina pectoris & vasospastic (Prinzmetal's) angina, Supraventricular tachyarrhythmias and rapid ventricular rates in atrial flutter or afib.
Action: Systemic vasodilation resulting in - BP. Coronary vasodilation resulting in - frequency & severity of attacks of angina.
Reduction of ventricular rate in afib or flutter.
Safe Dose:180–240 mg once daily as CD or XR capsules or LA tablets
Side Effects:
CNS: abnormal dreams, anxiety, confusion, dizziness, drowsiness, headache, nervousness, psychiatric disturbances, weakness
EENT: blurred vision, disturbed equilibrium, epistaxis, tinnitus
Resp: cough, dyspnea
CV: ARRHYTHMIAS, HF, peripheral edema, bradycardia, chest pain, hypotension, palpitations, syncope, tachycardia
GI: ↑ liver enzymes, anorexia, constipation, diarrhea, dry mouth, dysgeusia, dyspepsia, nausea, vomiting
Cardizem
Side Effects Cont.
Endo: gynecomastia, hyperglycemia
Hemat: anemia, leukopenia, thrombocytopenia
Metabolic: weight gain
MS: joint stiffness, muscle cramps
Neuro: paresthesia, tremor
Misc: gingival hyperplasia
GU: dysuria, nocturia, polyuria, sexual dysfunction, urinary frequency
Derm: STEVENS-JOHNSON SYNDROME, dermatitis, erythema multiforme, flushing, sweating, photosensitivity, pruritus/urticaria, rash
Med Interactions:
May ↑ digoxin levels.
Concurrent use with beta blockers, clonidine, digoxin, disopyramide, or phenytoin may result in bradycardia, conduction defects, or HF.
Grapefruit juice ↑ levels and effect.
Nursing Considerations: check serum dig levels, assess all systems daily, I&O, can take w/ or w/o food, monitor ECG, assess for rash, comply w/ other hypertension interventions
Colace 50mg QD PO
Class: laxative, stool softener
Promotes water into stool, resulting in softer feces.
May also promote electrolyte and water secretion in colon
Safe Dose: 50–400 mg in 1–4 divided doses
Side Effects:
EENT: throat irritation
GI: mild cramps, diarrhea
Derm: rashes
No drug interactions
Nursing Considerations:
Administer with a full glass of water or juice. May be administered on an empty stomach for more rapid results. laxatives should be used only for short-term therapy. Do not administer within 2 hr of other laxatives, especially mineral oil. Assess abdomen and stool
Coumadin 10 mg QD PO
Class: anticoagulant
Action- Prevention of thromboembolic events
Safe Dose:2–5 mg/day for 2–4 days; then adjust daily dose by results of INR
Side Effects:
GI: cramps, nausea
Derm: dermal necrosis
Hemat: BLEEDING
Misc: fever
Medication Interactions:
thrombolytics, NSAIDs, sulfonomides, chronic use of tylenol, and aspirin may + risk of bleeding
Many other drugs interact with coumadin
high vitamin K foods may antagonize anticoagulation
Nursing Considerations:
Monitor PT, INR & other clotting factors frequently, antidote is Vitamin K, have second practitioner check order before giving, monitor CBC, Stool, urine, hepatic function before and periodically
Depakene 500 mg BID PO
Class: anticonvulsants, vascular headache suppressant
Safe Dose: not to exceed 60 mg/kg/day; when daily dose exceeds 250 mg, give in divided doses
Nursing Considerations:
CBC, platetlets, bleeding time, hepatic function, serum ammonia before and during. Administer w/ or immediately after meals to minimize GI irritation
Side Effects:
CNS: SUICIDAL THOUGHTS, agitation, dizziness, headache, insomnia, sedation, confusion,depression
CV: peripheral edema
EENT: visual disturbances
GI: HEPATOTOXICITY, PANCREATITIS, abdominal pain, anorexia, diarrhea, indigestion, nausea, vomiting, constipation, ↑ appetite
Derm: alopecia, rashes
Endo: weight gain
Hemat: leukopenia, thrombocytopenia
Metabolic: HYPERAMMONEMIA
Neuro: HYPOTHERMIA, tremor, ataxia
Dyazide 37.5/25 mg QD PO
Class: diuretic potassium sparing/ antihypertensive/ thiazide diuretic
Safe Dose: 25–100 mg/day, 12.5–100 mg/day in 1–2 doses
Drug Interactions:
Hypokalemia ↑ risk of digoxin toxicity
Use with ACE inhibitors,indomethacin,angiotensin II receptor antagonists potassium supplements, or cyclosporine ↑ risk of hyperkalemia.
Take in the morning
Side Effects:
CNS: dizziness, drowsiness, lethargy, weakness
CV: arrhythmias, hypotension
GI: nausea, vomiting, hepatitis, anorexia, cramping
GU: erectile dysfunction, bluish urine, nephrolithiasis
Derm: photosensitivity, rash, Steven J S
F and E: hyperkalemia, hyponatremia
Hemat: blood dyscrasias
MS: muscle cramps
Misc: allergic reactions, pancreatitis
Digoxin 125 mcg QD PO
Class: anti-arrhythmic, intropics, digitalis glycosides
Safe Dose: Maintenance dose –0.125–0.5 mg/day
Action: Increased CO and slowing of the HR
Side Effects:
CNS: fatigue, headache, weakness
EENT: blurred vision, yellow or green vision
CV: ARRHYTHMIAS, bradycardia, ECG changes, AV block, SA block
GI: anorexia, nausea, vomiting, diarrhea
Hemat: thrombocytopenia
Metabolic: electrolyte imbalances with acute dig tox
Drug Interactions:
Thiazide and loop diuretics, piperacillin, ticarcillin, amphotericin B, corticosteroids, and excessive use of laxatives may cause hypokalemia which may ↑ risk of tox. Additive bradycardia may occur with B blockers. Thyroid hormones may ↓ thera effects.
Nursing Implications: give 1 hr before or 2 hr after high fiber meal. monitor apical pulse full min before, withhold HR <60, falls risk, serum electrolytes, give with meal or fluid, assess for toxicity
Percocet
Class: Opioid analgesic, opioid agonist-nonopioid anagelsic combo
Action: Binds to opiate receptors, decrease pain
Indications: moderate to severe pain
Onset: 10-15 minutes
Peak: 60-90 minutes
Contraindications: hypersensitivity to oxycodone or aspirin/acetaminophen/ibuprofen, bleeding disorders, liver or kidney disease, peptic ulcer disease, increased intracranial pressure
Interactions: alcohol, antihistamines increase CNS depression, kava kava
Adverse effects: confusion, sedation, dizziness, respiratory depression, constipation, orthostatic hypotension, dry mouth
Safe Dose: 5-10 mg q3-4hr
Assessment: PQRSTU pain questions, pain rating, BP, pulse RR, bowel function, administer Narcan for toxicity overdose
Administration: Can be given with food or milk
Teaching: Call for assistance when ambulating, make position changes slowly, turn cough and breathe deeply every 2 hours
Gentamicin Sulfate Class: Antibiotic, antiinfective
Action: bactericidal action
Indication: Treatment of serious bacterial infections when penicillins are contraindicated
Onset: rapid
Peak: 15-30 minutes
Contraindications: Hypersensitivity to gentamicin or other aminoglycosides, renal impairment, hearing impairment
Adverse effects: ataxia, vertigo, ototoxicity, nephrotoxicity, hypersensitivity reactions
Interactions: inactivated by penicillins and cephalosporins in patients with renal insufficiency
Safe Dose: IV: 1-2 mg/kg q8hr up to 6 mg/kg/day in 3 divided doses; once daily dosing: 4-7 mg/kg q 24 hr
Assessment: signs of infection, obtain specimen for C&S first, evaluate Cranial nerve VIII before & through therapy, monitor for vestibular dysfunction, monitor I&O & daily weight, assess for signs of superinfection, monitor urinalysis, specific gravity, BUN, creatinine, ALT, AST, bilirubin.
Admin: Keep pt well hydrated, dilute dose in 50-200 mL of D5W or 0.9% NaCl, Infuse slow 30 min-2 hr.
Teach: Report signs of hypersensitivity (tinnitus, rash, vertigo, dizziness), drink plenty of liquids.
Glucophage: Class: antidiabetics
Action: Decreases glucose production, increases sensitivity to insulin, maintenance of blood glucose
Indications: Management of Type II DM
Onset: unknown
Peak: 4-8 hours
Contraindications: hypersensitivity, metabolic acidosis, dehydration, kidney dysfunction, diagnostic procedures using IV contrast, HF, alcohol abuse
Adverse effects: Abdominal bloating, diarrhea, nausea, vomiting, lactic acidosis, hypoglycemia
Interactions: acute alcohol ingestion and IV contrast increase risk of lactic acidosis, digoxin, morphine, calcium channel blockers may compete for elimination pathways, furosemide may increase effects
Safe Dose: 500 mg BID up to 2000mg/day
Glucophage
Assessment: Observe for S/S of hypoglycemic reactions, assess for ketoacidosis or lactic acidosis in previously controlled patients who develop illness, monitor serum glucose, glycosylated hemoglobin periodically, BUN and creatinine, serum folic acid vitamin B12
Administration: Patients exposed to stress (surgery) may require insulin, administer with meals
Teaching: Follow prescribed diet, know S/S of hypoglycemia and hyperglycemia, test blood glucose, may cause unpleasant metallic taste, report stomach pain, diarrhea, nausea and vomiting to professional, carry a form of sugar and identification
Norvasc
Ther. Class: Antihypertensive (Ca Channel Blocker [-dipine])
- Ther. Effects: Systemic vasodilation (decreased bp), coronary vasodilation (decrease frequency and severity of anginal attacks. Used for Prinzmetals Angina.
- Half-life: 30-50hr
- Route: PO
- Onset: Unknown
- Peak: 6-9hr
- Duration: 24hr
- AR/SE: headache, peripheral edema
- Implementation: May be administered without food.
- Pt./Fam. Teaching: Take as directed. Do not skip or double doses. Avoid large amounts of grapefruit juice (6-8 glasses/day). Monitor pulse correctly and contact HCP if <50bpm. Change position slowly. May cause drowsiness. Good dental hygiene important to prevent tenderness, bleeding, and gum enlargement. Wear sunscreen to prevent photosensitivity rxns. Can continue to take if on nitrate or beta blocker. Continue with other antihypertensive therapy such as diet and exercise and monitor bp if used for HTN.
Norvasc
- Contraindications: Systolic BP <90, hx HF
- Interactions: Grapefruit juice increases effect
- Dose: 2.5mg QD. This is a normal starting dose. Can take up to 10mg/day.
- Assess: Monitor bp and pulse before therapy, during dose titration, and periodically during therapy. Monitor ECG periodically. Monitor I&O and daily wt. Assess for s/s of HF (peripheral edema, rales/crackles, dyspnea, wt. gain, jugular venous distention). Assess location, duration, intensity, and precipitating factors to anginal pain.
- Labs: Total serum Ca concen. is not affected by Ca channel blockers.
Lipitor
Ther. Class: Lipid lowering agent (-statin)
- Ther. Effects: Lowering of total cholesterol, LDL, and triglycerides (reducing risk of MI and stroke). Slightly increases HDL. Slows progression of coronary atherosclerosis.
- Half-life: 14hr
- Route: PO
- Onset: Unknown
- Peak: Unknown
- Duration: 20-30hr following discontinuation
- AR/SE: Abd. cramps, constipation, diarrhea, flatus, heartburn, rash, RHABDOMYOLYSIS, HYPERSENSITIVITY RXNS (ANGIONEUROTIC EDEMA), MUSCLE TENDERNESS.
- Dose: 20mg QD is a safe dose
- Contraindications: Acute liver disease
- Interactions: May slightly increase dig. levels. Grapefruit juice increases levels and risk of rhabdomyolysis.
- Assess: Diet hx especially fat consumption
Lipitor
- Labs: Serum cholesterol and triglycerides before therapy, 2-4wks after therapy begins, and periodically throughout therapy. Monitor AST and ALT prior to initiation. If muscle tenderness occurs, CPK levels should be monitored.
Implementation: May be given w/o food. Avoid grapefruit juice to decrease risk of tox.
- Pt./Fam. Teaching: Take as directed. Do not skip dose or double dose. Avoid drinking more than 1 qt. of grapefruit juice/day. Should be used with exercise and diet restrictions and smoking cessation. Notify HCP if muscle pain, weakness, or tenderness occurs (esp. if with fever or malaise).
Lasix: Ther. Class: Diuretic (loop diuretic)
- Ther. Effects: Diuresis and subsequent mobilization of excess fluid (edema, pleural effusions). Decreased bp.
- Half-life: 30-60min, Route: PO, Onset: 30-60min
- Peak: 1-2hr, Duration: 6-8hr
- AR/SE: STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, dehydration, hypocalcemia, hypochloremia, hypokalemia, hypomagnesemia, hyponatremia, hypovolemia, metabolic akalosis, APLASTIC ANEMIA, AGRANULOCYTOSIS.
- Dose: 30mg BID Recommended as 20-80 mg/day which may be repeated 6-8hr later. 30mg BID for a total of 60mg daily is a safe dose.
- Contraindications: Cross sensitivity with thiazides and sulfonamides.
- Interactions: Hypokalemia may increase risk of dig toxicity and arrhythmia. NSAIDs decrease effects.
- Assess: Assess fluid status (monitor daily wt, I&O, edema, lung sounds, skin turgor, mucous membranes). Notify HCP if thirst, dry mouth, lethargy, weakness, hypotension, or oliguria occur. Monitor bp and pulse before and during admin.
Lasix
- Pt./Fam. Teaching: Take as directed. Do not double doses. Change positions slowly. High K diet. Contact HCP if weight gain of more than 3lbs/day. Use sunscreen to prevent photosensitivity rxns. **Contact HCP immediately if rash, muscle weakness, cramps, nausea, dizziness, numbness, or tingling extremities occurs. Diabetics should monitor glucose levels closely bc it may increase.
**Assess pts. on dig. for anorexia, nausea, vomiting, muscle cramps, paresthesia, and confusion (dig toxicity bc of hypokalemia). Assess for tinnitus and hearing loss. **Assess for skin rash frequently. May be life threatening.
- Labs: Monitor for decreased electrolytes, renal and hepatic function (increased BUN, creatinine, and uric acid), and monitor for increased serum glucose.
- Implementation: Give 2nd dose no later than 5pm to minimize disruption of sleep cycle. May be taken with food or milk. Tabs may be crushed.
Heparin -Ther. Class: Anticoagulant
- Ther. Effects: Prevention of thrombus formation and prevention of extension of existing thrombi.
- Half-Life: 1-2hr, Route: SQ, Onset: 20-60min
- Peak: 2hr, Duration: 8-12hr
- AR/SE: BLEEDING, HEPARIN INDUCED THROMBOCYTOPENIA, anemia
- Dose: 8.000 Units Q12h should really be given q8h. 1200 Units Q12h is a very low dose and not therapeutic.
- Contraindications: Uncontrolled bleeding, severe thrombocytopenia, open wounds.
- Interactions: Concurrent use of thrombolytic increases bleeding. Dig, tetracyclines, nicotine, antihistamines decrease effects.
- Assess: Signs of bleeding and hemorrhage (bleeding gums, nose bleed, bruising, black tarry stools, decreased hct or bp). Assess for thrombosis. Monitor pt. for chills, fever, urticaria. Observe inject site for hematomas, ecchymosis, or inflammation.
- Labs: Monitor aPTT (30 min before each dose) and hct. Monitor platelet count every 2-3 days.
- Implementation: Administer as deep tissue. Alternate sites btw arm
Lantus U100 Insulin - Ther. Class: Hormones
- Ther. Effects: Control of hyperglycemia in diabetics
- Half-life: 5-6min, Route: SQ, Onset: 3-4hr
- Peak: No peak (relatively constant effect over time)
- Duration: 24hr
- AR/SE: HYPOGLYCEMIA, ALLERGIC RXNS (ANAPHYLAXIS)
- Dose: range is 2-100 units/day so dose of 6 units Qam is safe dosage.
- Contraindications: Hypoglycemia
- Interactions: Beta blockers mask s/s of hypoglycemia. Corticosteroids, thyroid supplements, estrogen may increase insulin requirements. Alc., Ace inhibitors (-prils), MAOIs may decrease insulin requirements.
- Assess: Symptoms of hypoglycemia include restlessness, tingling in hands and feet, chills, cold sweats, confusion, difficulty concentrating, drowsiness, nightmares, tremor, weakness. Symptoms of hyperglycemia include confusion, drowsiness, flushed dry skin, polyuria, unusual thirst. Monitor body weight periodically.
Lantus U100 Insulin
- Pt./Fam. Teaching: Instruct proper administration and selection of injection site. Therapy is long term. Instruct proper glucose testing. Emphasize diet and exercise guidelines. Carry source of sugar and ID card.
- Antidote: IV glucose, glucagon, or epinephrine.
- Precautions: High alert med BE CAREFUL. Do not mix with other insulins. Prior to withdrawing, rotate vial between palms. Store in cool place up to 28 days.
- Labs: Monitor blood glucose every 6hr. A1C can be monitored every 3-6 months.
Imodium - Ther. Class: Antidiarrheals
- Ther. Effects: Relief of diarrhea.
- Half-Life: 10.8hr
- Route: PO
- Onset: 1hr
- Peak: 2.5-5hr
- Duration: 10hr
- AR/SE: drowsiness, constipation
- Dose: 2mg after each loose stool is a safe dose
- Contraindications: Abd. pain of unknown cause, alc. intolerance.
- Interactions: Kava-kava, valeria, skullcap, chamomile, hops all increase CNS depression.
- Assess: Frequency and consistency of stools and bowel sounds. Fluid and electrolyte balance. Skin turgor.
- Implementation: Administer with clear fluids to prevent dehydration.
- Pt./Fam. Teaching: Frequent mouth rinses, good oral hygiene, sugarless gum/candy may relieve dry mouth. Avoid using alc.
Lopressor -Ther. Class: Antianginal, antihypertensive (beta blocker [metaprolol])
- Ther. Effects: Decreases bp and hr. Decreases frequency of angina pectoris. Decreases rate of cardiovascular mortality and hospitalization in pts. w/ heart failure.
- Half-life: 3-7hr, Route: PO (max effects on bp may not occur for 1 week)
- Onset: 15min, Peak: Unknown
- Duration: 6-12hr
- AR/SE: fatigue, weakness, BRADYCARDIA, HF, PULMONARY EDEMA, erectile dysfunction
- Dose: 50mg QD this is a safe dosage.
- Pt./Fam. Teaching: Instruct to take med at same time each day. Do not skip or double up on doses. Abrupt withdrawal may cause arrhythmias, hypertension, and myocardial ischemia. Check pulse daily and bp biweekly. May cause drowsiness. Change position slowly. Diabetics should monitor blood glucose more closely (med will not block sweating as a sign of hypoglycemia). Carry ID card. Continue additional therapies for hypertension (diet and exercise).
Lopressor

Assess: Monitor bp, ECG, and pulse frequently. If hr is <40 administer atropine IV. Monitor I&O and daily wts. Assess routinely for s/s of HF (dyspnea, rales/crackles, wt gain, peripheral edema, jugular venous distention). Assess frequency and characteristics of anginal attacks.
- Contraindications: Uncompensated HF, pulmonary edema, cardiogenic shock, bradycardia, heart block
- Interactions: Anesthesia, phenytoin, verapamil may increase myocardial depression. Concurrent admin of thyroid may decrease effectiveness. May alter effectiveness of insulin.
- Labs: May increase BUN, K, blood glucose, AST, ALT, LDH, triglycerides, and uric acid.
- Implementation: Take apical impulse before admin. If <50bpm or arrhythmic, withhold med and notify HCP. Admin with meals or directly after eating. ER tabs must be taken whole.
Morphine - Ther. Class: Opiod agonist
- Ther. Effects: Decrease in severity of pain.
- Half-life: 2-4hr (adults), Route: IM or IV
- Onset: 10-30min (IM) or rapid (IV)
- Peak: 30-60min (IM) or 20min (IV)
- Duration: 4-5hr for both routes
- AR/SE: Confusion, sedation, RESPIRATORY DEPRESSION, hypotension, constipation
- Dose: 4mg Q4h is a safe dose. Usual dose is 4-10mg Q3-4hr.
- Contraindications: Use cautiously in head trauma, seizure, hypothyroidism, hx of substance abuse.
- Interactions: Use with extreme caution in pts. receiving MAOIs w/i 14 days prior. Kava-kava, valerian, chamomile can increase CNS depression.
- Assess: Assess type, location, and intensity of pain prior to and 1hr (IM) or 20 (IV) following admin. **Assess level of consciousness, bp, pulse, and respirations before and periodically during admin. If RR is <10/min assess level of sedation. Prolonged use may lead to tolerance. Assess bowel function routinely.
Morphine

- Implementation: Do not confuse with hydromorphone. Have 2nd HCP check order, dosage calc, and infusion pump settings. Coadmin with nonopiod analgesics may permit lower dosing.
- IV admin: solution should be colorless. dilute with at least 5mL of sterile water or 0.9% NaCl. Concentration is 0.5-5mg/mL. Administer 2.5-15mg over 5min. May be administered via PCA.
- Pt./Fam. Teaching: May cause drowsiness and dizziness. Change positions slowly. Avoid concurrent use with alc. or other CNS depressants. Turn, couch, breathe deeply every 2hr.
- Antidote: Naloxone (Narcan)
Nitro Derm Patch- Ther. Class: Antianginals
- Ther. Effects: Relief or prevention of anginal attacks. Increase cardiac output. Reduced bp.
- Half-life: 1-4min, Route: Patch, Onset: 40-60min
- Peak: Unknown, Duration: 8-24hr
- AR/SE: Dizziness, hypotension, tachycardia
- Dose: 0.3mg/hr QD is a safe dose. Patch should be worn 12-14hr/day and taken off for 10-12hr/day.
- Contraindications: Severe anemia, pericardial tamponade, constrictive peridcarditis.
- Assess: Assess location, duration, intensity, and precipitating factors of anginal pain. Monitor bp and pulse before and after admin.
- Implementation: Rotate sites to prevent skin irritation. Remove patch and clean site before next application. Apply to any hairless site with firm pressure especially around edges. Apply a new does if the patch becomes loose or falls off. They are waterproof. Do not alternate brands between patches bc dosing may not be equal. Remove patch before MRI, cardioversion, or defibrillation to prevent burns.
Nitro Derm Patch

- Interactions: Concurrent use of nitrates in any form with sildenafil, taladafil, and vardenafil increase risk of potentially fatal hypotension.
- Pt./Fam. Teaching: Take as directed. Take missed dose asap unless next dose is scheduled within 2hr. Do not discontinue abruptly. Change positions slowly. First dose should be taken while sitting. Avoid concurrent use of alc. Headache is common side effect and can take aspirin or acetaminophen. Notify HCP if headache is severe or persistent or if dry mouth or blurred vision occurs.
NPH Insulin- Ther. Class: Antidiabetics, Hormones
Ther Effects: Control of hyperglycemia in diabetics
- Half-life: Unknown, Route: SQ, Onset: 2-4hr
- Peak: 4-10hr, Duration: 10-16hr
- AR/SE: HYPOGLYCEMIA, ALLERGIES (ANAPHYLAXIS)
- Contraindications: Hypoglycemia
- Interactions: Beta blockers, clonidine, and reserpine may mask s/s of hypoglycemia. Coticosteroids, thyroid supplements, estrogens, may increase insulin requirements. Alc, ACE (-pril) inhibitors, MAOIs may decrease insulin requirements.
- Labs: Monitor blood glucose every 6hr during therapy. A1C may be monitored every 3-6mo.
- Antidote: IV glucose, glucagon, or epinephrine
- Implementation: Check type, dose, expiry with another licensed nurse. Do not confuse Humulin with Humalog or Novolin with Novolog. Rotate vial before withdrawing. **Administer within 30-60min before a meal.
- Pt./Fam. Teaching: proper tech for administration. Discuss importance of not changing brands or sharing pens. Therapy is long term. Instruct proper blood glucose test and ketones. Importance of diet. Carry a source of sugar and ID card
NPH Insulin
- Dose: 15 units Qam. Safe dosage is 0.5-1 unit total insulin/kg/day (dosing depends on wt. of pt.)
- Assess: Assess for s/s of hypoglycemia (restlessness, tingling, chills, cold sweats, confusion, difficulty concentrating, drowsiness, nightmares, tremors, weakness) and hyperglycemia (confusion, drowsiness, flushed dry skin, fruit like breath, polyuria, unusual thirst). Monitor body wt.
Potassium Chloride, Prendisone, Prilosec, Regular U100 Insulin, Rocephin, Synthroid, Toradol, Trivelent inactivated influenza vaccine, vancomycin, zithromax
See Nursing Central 23-32
Advil, Amoxicillin, Cardizem, Colace, Coumadin, Depakene, Dyazide, Digoxin, Percocet, Gentamicin sulfate, Glucophage
See Nursing Central 1-11
Heparin, Imodium, Lantis U100 Insulin, Lasix, Lipitor, Lopressor, Morphine, Nitro Derm Patch, Norvasc, NPH Insulin
See Nursing Cental 12-22
Heparin
- Pt./Fam. Teaching: Report any unusual bleeding or bruising immediately. Do not take aspirin or NSAIDs while on heparin. Avoid activities leading to injury. Use soft tooth brush, and an electric razor.