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34 Cards in this Set
- Front
- Back
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Alpha1 Locations
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1. Eye
2. Arterioles (skin, viscera, mucous membranes) 3. Veins 4. Sex organs, male 5. Prostatic capsule 6. Bladder |
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Alpha2 Locations
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1. Presynaptic nerve inhibition of transmitter release terminals
2. Postsynaptic in the central nervous system |
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Beta1 Locations
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1. Heart
2. Kidney |
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Beta2 Locations
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1. Arterioles (heart, lung, skeletal muscle)
2. Bronchi 3. Uterus 4. Liver 5. Skeletal muscle |
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Dopamine Locations
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1. Kidney
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Eye
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1. Alpha1
2. Contraction of the radial muscle of the iris causes mydriasis (increased pupil size) |
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Arterioles
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1. Alpha1
2. Skin, viscera, and mucous membranes 3. Constriction A. Beta2 B. Heart, lung, and skeletal muscle C. Dilation |
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Veins
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1. Alpha1
2. Constriction |
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Sex organs, male
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1. Alpha1
2. Ejaculation |
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Prostatic capsule
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1. Alpha1
2. Contraction |
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Bladder
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1. Alpha1
2. Contraction of trigone and sphincter |
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Heart
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1. Beta1
2. Increase rate |
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Kidney
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1. Beta1
2. Release of renin A. Dopamine B. Dilation of kidney vasculature |
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Bronchi
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1. Beta2
2. Dilation |
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Uterus
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1. Beta2
2. Relaxation |
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Liver
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1. Beta2
2. Glycogenolysis |
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Skeletal Muscle
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1. Beta2
2. Enhanced contraction, glycogenolysis |
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Alpha1 General
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1. Vasoconstriction
2. Ejaculation 3. Contraction of bladder neck and prostate |
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Alpha2 General
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1. Located in presynaptic junction
2. Minimal clinical significance |
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Beta1 General
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A.Heart
1. Increases heart rate 2. Increases force of contraction 3. Increases velocity of conduction in atrioventricular (AV) node B. Kidney 1. Renin release |
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Beta2 General
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1. Bronchial dilation
2. Relaxation of uterine muscle 3. Vasodilation 4. Glycogenolysis |
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Dopamine General
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1. Dilates renal blood vessels
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Adrenergic Agonist
Epinephrine |
1. Receptor Specificity
-Alpha1, Alpha2, Beta1, Beta2 2. Chemical Classification -Catecholamine 3. Therapeutic Uses -Elevates BP, Mydriasis, Restores cardiac function in arrest, Bronchial dilation in asthma, Treatment for anaphylactic shock |
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Adrenergic Agonist:
Norepinephrine |
1. Receptor Specificity
-Alpha1, Alpha2, Beta1 2. Chemical Classification -Catecholamine 3. Therapeutic Uses -Hypotensive states, Cardiac arrest |
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Adrenergic Agonist:
Isoproterenol |
1. Receptor Specificity
-Beta1, Beta2 2. Chemical Classification -Catecholamine 3. Therapeutic Uses -AV heart block or arrest, Bronchodilation (Asthma - not used anymore), Bronchospasm (during anesthesia) |
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Adrenergic Agonist:
Dopamine |
1. Receptor Specificity
-Alpha1, Beta1, and Dopamine 2. Chemical Classification -Catecholamine 3. Therapeutic Uses -Increase cardiac output, increase renal perfusion, preserve renal function with ARF |
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Adrenergic Agonist:
Dobutamine |
1. Receptor Specificity
-Beta1 2. Chemical Classification -Catecholamine 3. Therapeutic Uses -Congestive Heart Failure (CHF) |
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Adrenergic Agonist:
Phenylephrine |
1. Receptor Specificity
-Alpha1 2. Chemical Classification -Non Catecholamine 3. Therapeutic Uses -Reduce nasal congestion, Elevate BP, Dilate pupils, |
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Adrenergic Agonist:
Terbutaline |
1. Receptor Specificity
-Beta2 2. Chemical Classification -Non Catecholamine 3. Therapeutic Uses -Asthma, Delay of pre-term labor |
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Adrenergic Agonist:
Ephedrine |
1. Receptor Specificity
-Alpha1, Alpha2, Beta2 2. Chemical Classification -Non Catecholamine 3. Therapeutic Uses -Nasal congestion |
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What are the therapeutic applications for Alpha-Adrenergic blockade?
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1. Essential hypertension
2. Benign prostatic hyperplasia 3. Pheochromocytoma 4. Raynaud's Disease |
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What are the Alpha-Adrenergic Antagonists II medications?
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1. Prazosin
2. Silodosin 3. Terazosin 4. Doxazosin 5. Tamsulosin 6. Alfuzosin 7. Phentolamine 8. Phenoxybenzamine |
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What are the therapeutic applications for Beta-Adrenergic blockade?
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1. Angina pectoris
2. Heart failure 3. Hyperthyroidism 4. Migrane 5. Pheochromocytoma 6. Glaucoma |
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What are the Beta-Adrenergic Antagonist II medications?
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1. Atenolol
2. Propranolol 3. "several others that end with -olol" |
