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30 Cards in this Set

  • Front
  • Back
What is the development of the central nervous system known as?
Neurulation
Along what axis do the major divisions develop?
Rostrocaudal
Which regions develop to give the forebrain (prosencephalon)?
Telencephalon and diencephalon
Which regions develop to give the midbrain?
Mesencephalon
Which regions develop to give the hindbrain (rhombencephalon)?
Metencephalon and myelencephalon
Where is CSF made?
Choroid plexus within the ventricles
What are the 3 layers of meninges?
From out to in:
Dura mater
Arachnoid mater
Pia mater
Where is CSF found?
Fills the entirety of the lumen of the CSF 'tube'
Also found between the arachnoid mater and pia mater
What is the purpose of the meninges?
Cover and protect the brain and spinal cord
Protect organs from rubbing against bones of skull and spine
What is anencephaly?
The head end of the neural tube fails to close
Infant is born with no head and is usually stillborn or dies within hours
What are the two types of spina bifida and what are they?
Occulta- fairly common
Cystica- more severe; herniation of meninges +/- spinal cord through opening in the spinal canal
What are the regions of the spinal cord?
Cervical, thoracic, lumbar, sacral
Correspond to vertebrae
Where is the lumbar cistern and what does is allow?
L3/L4
L4/L5
Safe to do a CSF tap here
Sympathetic nervous system regions
T1-T6: chest, neck and head
T6-T12: abdomen
T12+: pelvis
Which regions make up the hindbrain?
Pons, cerebellum and medulla
What are the functions of the pons and medulla?
Hearing and balance
Pons inputs to the cerebellum

Site of nuclei which cause basic functions e.g. breathing, heart rate
What is the function of the cerebellum?
Assesses body position and compares to motor command. Sees if there is an error between intention of brain and action of body.
Posture, eye movement, measuring, timing
What is caused by damage to the cerebellum?
Ataxia
Clumsiness, difficultly of movement
What are the functions of the midbrain?
Dorsal: colliculi- vision, hearing
Ventral: occulomotor nuclei, dopaminergic neurons
What disorders are associated with midbrain damage?
Eye movement defects
Parkinson's disease
What is the embryological feature that becomes the forebrain?
Embryonic dorsal diencencephalon
Where is the thalamus and what is its function?
Forebrain
Sensory relay to the cortex
Site of consciousness
Damage- coma
Where are the basal ganglia and what are the functions?
Forebrain- above thalamus
Modulate critical activity
Cognitive reward, learning and motivation
What is the cortex?
Outermost layer of the brain
Covers cerebrum
Grey matter
How is the cerebral cortex organised?
6 horizontal layers
Each layer is a different distribution of cell types
What are cortical maps?
Sensory and motor
Areas that have been identified as performing a specific function
What is a property of the maps?
Map plasticity- maps are flexible
They can change with learning
What can be affected with frontal lobe damage?
Association cortex
Character and personality
Gaze control
Learned tasks
What is Broca's aphasia and it's symptoms?
Speech disorder associated with left side cortex damage
Telegraphic speech, meaning spared
Comprehension normal
Can't speak, can understand
What is Wernicke's aphasia and it's symptoms?
Speech disorder associated with cortex damage
Speech pattern is normal
No meaning or comprehension
Can speak, can't understand