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77 Cards in this Set
- Front
- Back
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chlorpromazine s/e
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main side effects are shuffling gait and corneal deposits
(it's an anti-psychotic that blocks D2 receptors) [do the prom shuffle] |
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which step of collagen formation requires vit c
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hydroxylation of proine and lysine
[think Hy-C] |
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what is the site of ear injury from listening to loud music/ noise?
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sterociliated cells in the Organ of Corti
[think of listening to loud ORGAN music on the STERO] |
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my extended def of CREST
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Calcinosis, Centromere Ab, Collagen in tissues
Raynauds, Right-side heart failure Esophageal dismotility Sclerodactaly Telangiectasia, T-cell prolif, TGF-beta inc. |
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what embryologic structure is the PDA derived from
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6th aortic arch
[think: 6 looks like backwards d] |
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how do aminoglycosides confer resistance
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transfer chemical groups so ATB can't bind
[like changing clothes to disguise themselves] |
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how does penicillin confer resistance
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1) beta-lactamases
2) low affinity penicillin binding protein [like producing a protective covering that disintegrates incoming chemical warfare & making heat-seeking missals that seek out and destroy incoming fire] |
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how does vancomycin confer resistance
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alter the D-ala D-ala cell wall structure
[like changing the fortress wall from brick to steel] |
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s/e of phenytoin
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induces P450 so inc. metabolism drugs metabolized by P450
ataxia nystagmus gingival hyperplasia coarsening of factial features hirsutism |
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drugs most commonly used to tx staph aureus
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nafcillin
methicillin oxacillin [use NAF to tx STAPH] |
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what does acid fast stain stain for?
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mycolic acid
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if your're sitting or standing where will aspirated foreign body go
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posterobasal segment of right lower lobe
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if lying down on one's back where will aspirated foreign body go
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superior segment right lower lobe
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if lying on right side where will aspirated foreign body go
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middle or posterior right UPPER lobe
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if lying on left side where will aspiraed foreign body go
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lingula
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screening test of choice for pulmonary embolus
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ventilation perfusion scan (will have ventilation but no perfusion)
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confirmatory test for pulmonary embolus
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pulmonary angiogram
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what's caplan syndrome
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combo of rheumatoid arthritis (rheumatoid nodules) in lung plus pneumoconiosis (silicosis, asbestosis or cole worker's diz)
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most common association with asbestos
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fibrous plaque on pleura not cancer!
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most common & 2nd most common cancer assoc with asbestos
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1= primary lung cancer
2= mesothelioma |
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where in the bronchial tree does gas exchange occur
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respiratory bronchiole, respiratory alveolar duct and alveoli
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most common cause of spontaneous peritonitis in kids
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strep pneumo
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most common cause of spontaneous peritonitis in adults
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e. coli
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courvoisier's sign
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painless jaundice
light colored stools palpable GB |
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physical characteristics of Wilms tumor
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aniridia and hemihypertrophy of an extremity
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spikes associated with which glomerular disease
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membranous glomerulonephritis
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which glomerular disease is Hep B assoc with
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memBranous glomerulonephritis
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which glomerular disease is Hep C assoc with
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membranoproliferative glomerulonephritis
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subendothelial despisit seen with which glomerular disease
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type I membranoproliferative glomerulonephritis
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Hep C assoc with which rheumatic disease
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cryoglobulinemia
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tram tracks assoc with which glomerular disease
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membranoproliferative glomerulonephritis
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what components are in the immune complexes of type II membranoproliferative glomerulonephritis
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C3 and anti-C3 Ab
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marker for most common testicular tumor in child?
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AFP (yolk sac tumor)
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psamomma bodies assoc with
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papillary thyroid cancer,
serous cystadenocarcinoma meningiomas |
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most common ovarian tumors
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serous cystadenoma and serous cystadenocarcinoma
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most likely cause of estrogen producing tumor
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granulosa cell tumor
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meig's syndrome
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ovarian fibroma,
ascites, right side pleural effusion |
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most common bilateral tumor of the breast
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lobular carcinoma (in terminal lobules, where milk comes from)
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most common bilateral tumor in ovaries
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serous cystademomas/ cystadenocarcinomas
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most common type of breast cancer
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infiltrating ductal carcinoma
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most common cause of bloody nipple discharge in woman under 50
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intraductal papilloma (benign)
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indian filing assoc with what
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invasive ductal carcinoma
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what cancer is assoc with peau d'orange skin
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inflammatory carcinoma
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what's paget's disease of the breast
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ductal carcinoma that has infiltrated the epithelium of the nipple and areola
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signs of GH def in adult
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loss of muscle mass &
fasting hypoglycemia (GH inc. aa uptake and gluconeogenesis) |
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what's binding protein for cortisol
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transcortin
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what's binding protein for Ca?
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albumin
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what's binding protein for Fe
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transferrin
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what's binding protein for Cu?
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ceruloplasmin
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midline cyst in throat
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thyroglossal cyst
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cyst in anterolateral neck
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branchiocleft cyst
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mech for tetany in alkalosis
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in alkalosis, H+ decreased
more basic amino acids present (have COO- groups vs. COOH groups) ionized Ca2+ binds the COO- groups less free Ca2+ means less available for action potential propagation lower threshold for action potentials--> tetany |
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organism causing meningitis with petechial lesions
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N meningitidis
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what complement components predispose to disseminated gonorrhea
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final pathway components (C5-C9) so you can't form a MAC attack
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typically associated with unilateral Bell's Palsy
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Herpes Simplex
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typically associated with bilateral Bell's Palsy
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Lyme's disease
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what diseases associated with the Ixodes tick
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Lyme's disease & Babesiosis
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presentation of Babesiosis
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hemolytic anemia
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what id the defect in Osteogenesis imperfecta
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defect in synthesis of type I collagen
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what's osteochondroma
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most common benign bone tumor
causes protuberance of the bone with a cartilagenous cap |
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signs and sx of osteogenic sarcoma
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sun burst appearance
Codman's triangle (created from new bone raising subperiosteum) Rb suppresor gene relationship on chromosome 13 knee area (metaphysial origin) adolescent |
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most common malignant bone tumor
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chondrosarcoma (usually in hip)
[think of Chondra with big HIPs) |
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diseases assoc with triplet repeats
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Myotonic dystrophy
Huntington's Fragile X Friedrich's ataxia |
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what type of hypersensitivity is contact dermatitis
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type IV
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rash in Christmas tree distribution
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pityriasis rosea (non-pruritic, oblong, not fungal)
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bugs with tumbling motility
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listeria, trichomonas
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antidote for digoxin o/d
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anti-digoxin Fab
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histology of small cell carcinoma
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neuroendocrine cells (small dark blue)-- looks like disorganized blue rice
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first line tx for partial seizures
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carbamazepine (simple and complex)
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first line for tonic-clonic seizures
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phenytonin
carbamazepine valproic acid (think: you can use anything for the worst type of seizure) |
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myoclonic seizure tx
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valproic acid
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second line for absence seizure
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valproic acid
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synaptophysin stains for
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neurons
[think: syNEURONphysin] |
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what are holocrine glands
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found with sebaceous glands. secreted their whole cell conten.
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what are eccrine glands
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sweat glands for most of body
aka merocrine glands |
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what are apocrine glands
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sweat glands in fat of areolae, axillae, genital areas-- the ones that make you stink (when mixed with bacteria on skin)!
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what drains into the brachiocephalic vv and where do they drain to
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jugulars and subclavian veins drain to the brachiocephalics
brachiocephalics em |
