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49 Cards in this Set
- Front
- Back
The process of growing old
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Aging
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What are the evidence of aging
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1. Decline in hemeostatic efficiency
2. Increasing probability that reaction to injury will not be successful |
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It is the scientific study of factors impacting the normal aging process and the effects of aging.
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Gerontology
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It is the branch of medicine concerned with the illnesses of old age and their care.
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Geriatrics
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It is the maximum survival potential, the inherent natural life of species.
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Life span
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Human life span
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110-120 years
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It is the number of years of life expectation from year of birth.
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Life expectancy
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T or F: Women live 6.6 years longer than men.
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True
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Life expectancy of people in the United States
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75.8 years
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It is the last stage of adulthood through death.
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Senescence
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Three categories of elderly
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Young elderly
Old elderly Old, old elderly (Old and frail elderly) |
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Age range to be considered young elderly
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65-74 years
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Age range to be considered old elderly
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75-84 years
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Age range to be considered Old, old elderly
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>85 years
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Factors contributing to increased life expectancy
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1. Advances in healthcare, improved infectious control
2. Advances in infant/child care, decrease mortality rates 3. Improvements in nutrition and sanitation |
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Leading causes of death in persons over 65 (in order of frequency)
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1. CHD
2. CA 3. CVD 4. COPD 5. Pneumonia/flu |
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Leading causes of disability/chronic conditions (mordibity) in persons over 65, in order of frequency
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1. Arthritis
2. HTN 3. Hearing impairments 4. Heart impairments 5. Cataracts and chronic sinusitis 6. Orthopedic impairments 7. DM and visual impairments 8. One of more chronic conditions |
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What percentage of total health care expenditures do older persons account?
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36%
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What percentage of hospital stays and hospital days of care do older persons account?
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33% of hospital stays
44% of hospital days |
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What are the theories of aging?
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1. Biological theories
2. Environmental theories (stochastic or nongenetic) 3. Psychological theories 4.Sociological theories |
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Examples of cellular changes during aging
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1. Fragmentation of Golgi apparatus and mitochondria
2. Decrease in cell capacity to divide and reproduce 3. Arrest of DNA synthesis and cell division |
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Examples of tissue changes during aging
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1. Accumulation of pigmented materials, lipofuscins
2. Accumulation of lipids and fats 3. Connective tissue changes (decreased elastic content, degredation of collagen, presence of pseudoelastins) |
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Examples of Organ changes during aging
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1. Decrease in functional capacity
2. Decrease in hemeostatic efficiency |
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This theory of aging states that genes are programmed to modulate aging changes
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Genetic
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Term used for premature aging syndromes
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Progeria
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Progeria of Childhood
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Hutchinson-Gilford syndrome
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Progeria of young adults
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Werner's syndrome
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This theory states that functional deterioration within cells is due to limited number of genetically programmed cell doublings or cell replication
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Doubling/biological clock (Hayflick's limit theory)
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These are highly reactive, toxic forms of oxygen produced by mitochondria
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Free radicals
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Effects of free radicals to the cell/body
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1. Cause damage to cell membranes and DNA cell replication
2. Interefere with cell diffusion and transport, resulting in decreased O2 delivery and tissue health. 3. Decrease cellular integrity, enzyme activities. 4. Result in cross-linkages (chemical bonding of elements not generally joined together) 5. Results in accumulation of aging pigments, lipofuscins. 6. Can trigger pathological changes (atherosclerosis in blood vessel wall or cell mutations in CA) |
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These are errors in the synthesis of proteins (DNA, RNA) that lead to aging changes
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Cell mutation (Intrinsic Mutagenensis)
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This theory states that functional decrements in neurons and their associated hormones leads to aging changes
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Hormonal theory
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Primary regulators and timekeepers of aging
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Hypothalamus
Pituitary gland Adrenal gland |
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This is the master hormone of the body and controls rate of protein synthesis and metabolism
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Thyroxine
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Protective hormones
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Estrogen
Growth hormone Adrenal DHEA (dehydroepiandrosterone) |
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Effects of Increased stress hormone (Cortisol)
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Can damage brain's memory center, the hippocampus, and destroy immune cells
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What are some changes during aging according to Immunity theory?
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Thymus size decreases and becomes less functional
Bone marrow cell efficiency decreases which results in steady decrease in immune responses during adulthood Tcells, become less able to fight foreign organisms B cells become less able to make antibodies Autoimmune diseases increase with age |
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This theory states that aging is caused by an accumulation of insults from the environment
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Environmental Theories (Stochastic or nongenetic)
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Examples of environmental toxins
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UV rays
Cross linking agents (saturated fats) Toxic chemicals (metal ions, Zn, Mg) Radiation Viruses |
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T or F: Toxins can result in errors in protein synthesis and DNA synthesis/genetic sequences (error theory), cross linkage of molecules, mutations
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True
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This theory states that homeostatic imbalances alter structural and chemical composition in the body
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Stress theory
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Three stages of General Adaptation Syndrome
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1. Alarm stage
2. Resistance stage 3. Exhaustion stage |
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T or F: Stress theory is closely linked to hormonal theory
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True
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What does Erikson's bipolar theory of lifespan development (Stages of later adulthood) states?
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Integrity vs. Despair
A person gets a sense of integrity if life is viewed with satisfaction. A person will feel despair if life is viewed with regrets. |
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This theory states that life experience/lifestyles influence aging process.
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Sociological theory
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This theory states that older persons who are socially active exhibit improved adjustments to the aging process.
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Activity theory
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This states that reduction in social roles leads to further isolation and life dissatisfaction.
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Disengagement theory
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Term for increasing reliance on others for meeting physical and emotional needs.
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Dependency
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What is intergral model of aging
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Assumes that aging is a complex, multifactorial phenomenon in which some or all of the above processes may contribute to the overall aging of an individual and that aging is not adequately explained by any single theory.
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