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49 Cards in this Set

  • Front
  • Back
The process of growing old
Aging
What are the evidence of aging
1. Decline in hemeostatic efficiency
2. Increasing probability that reaction to injury will not be successful
It is the scientific study of factors impacting the normal aging process and the effects of aging.
Gerontology
It is the branch of medicine concerned with the illnesses of old age and their care.
Geriatrics
It is the maximum survival potential, the inherent natural life of species.
Life span
Human life span
110-120 years
It is the number of years of life expectation from year of birth.
Life expectancy
T or F: Women live 6.6 years longer than men.
True
Life expectancy of people in the United States
75.8 years
It is the last stage of adulthood through death.
Senescence
Three categories of elderly
Young elderly
Old elderly
Old, old elderly (Old and frail elderly)
Age range to be considered young elderly
65-74 years
Age range to be considered old elderly
75-84 years
Age range to be considered Old, old elderly
>85 years
Factors contributing to increased life expectancy
1. Advances in healthcare, improved infectious control
2. Advances in infant/child care, decrease mortality rates
3. Improvements in nutrition and sanitation
Leading causes of death in persons over 65 (in order of frequency)
1. CHD
2. CA
3. CVD
4. COPD
5. Pneumonia/flu
Leading causes of disability/chronic conditions (mordibity) in persons over 65, in order of frequency
1. Arthritis
2. HTN
3. Hearing impairments
4. Heart impairments
5. Cataracts and chronic sinusitis
6. Orthopedic impairments
7. DM and visual impairments
8. One of more chronic conditions
What percentage of total health care expenditures do older persons account?
36%
What percentage of hospital stays and hospital days of care do older persons account?
33% of hospital stays
44% of hospital days
What are the theories of aging?
1. Biological theories
2. Environmental theories (stochastic or nongenetic)
3. Psychological theories
4.Sociological theories
Examples of cellular changes during aging
1. Fragmentation of Golgi apparatus and mitochondria
2. Decrease in cell capacity to divide and reproduce
3. Arrest of DNA synthesis and cell division
Examples of tissue changes during aging
1. Accumulation of pigmented materials, lipofuscins
2. Accumulation of lipids and fats
3. Connective tissue changes (decreased elastic content, degredation of collagen, presence of pseudoelastins)
Examples of Organ changes during aging
1. Decrease in functional capacity
2. Decrease in hemeostatic efficiency
This theory of aging states that genes are programmed to modulate aging changes
Genetic
Term used for premature aging syndromes
Progeria
Progeria of Childhood
Hutchinson-Gilford syndrome
Progeria of young adults
Werner's syndrome
This theory states that functional deterioration within cells is due to limited number of genetically programmed cell doublings or cell replication
Doubling/biological clock (Hayflick's limit theory)
These are highly reactive, toxic forms of oxygen produced by mitochondria
Free radicals
Effects of free radicals to the cell/body
1. Cause damage to cell membranes and DNA cell replication
2. Interefere with cell diffusion and transport, resulting in decreased O2 delivery and tissue health.
3. Decrease cellular integrity, enzyme activities.
4. Result in cross-linkages (chemical bonding of elements not generally joined together)
5. Results in accumulation of aging pigments, lipofuscins.
6. Can trigger pathological changes (atherosclerosis in blood vessel wall or cell mutations in CA)
These are errors in the synthesis of proteins (DNA, RNA) that lead to aging changes
Cell mutation (Intrinsic Mutagenensis)
This theory states that functional decrements in neurons and their associated hormones leads to aging changes
Hormonal theory
Primary regulators and timekeepers of aging
Hypothalamus
Pituitary gland
Adrenal gland
This is the master hormone of the body and controls rate of protein synthesis and metabolism
Thyroxine
Protective hormones
Estrogen
Growth hormone
Adrenal DHEA (dehydroepiandrosterone)
Effects of Increased stress hormone (Cortisol)
Can damage brain's memory center, the hippocampus, and destroy immune cells
What are some changes during aging according to Immunity theory?
Thymus size decreases and becomes less functional
Bone marrow cell efficiency decreases which results in steady decrease in immune responses during adulthood
Tcells, become less able to fight foreign organisms
B cells become less able to make antibodies
Autoimmune diseases increase with age
This theory states that aging is caused by an accumulation of insults from the environment
Environmental Theories (Stochastic or nongenetic)
Examples of environmental toxins
UV rays
Cross linking agents (saturated fats)
Toxic chemicals (metal ions, Zn, Mg)
Radiation
Viruses
T or F: Toxins can result in errors in protein synthesis and DNA synthesis/genetic sequences (error theory), cross linkage of molecules, mutations
True
This theory states that homeostatic imbalances alter structural and chemical composition in the body
Stress theory
Three stages of General Adaptation Syndrome
1. Alarm stage
2. Resistance stage
3. Exhaustion stage
T or F: Stress theory is closely linked to hormonal theory
True
What does Erikson's bipolar theory of lifespan development (Stages of later adulthood) states?
Integrity vs. Despair
A person gets a sense of integrity if life is viewed with satisfaction. A person will feel despair if life is viewed with regrets.
This theory states that life experience/lifestyles influence aging process.
Sociological theory
This theory states that older persons who are socially active exhibit improved adjustments to the aging process.
Activity theory
This states that reduction in social roles leads to further isolation and life dissatisfaction.
Disengagement theory
Term for increasing reliance on others for meeting physical and emotional needs.
Dependency
What is intergral model of aging
Assumes that aging is a complex, multifactorial phenomenon in which some or all of the above processes may contribute to the overall aging of an individual and that aging is not adequately explained by any single theory.