Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/14

Click to flip

14 Cards in this Set

  • Front
  • Back
what kind of Organism is C.botulinum?
Gram (+ve)
spore forming rod
4 clinical forms:
foodborne
wound
infant
adult infectious botulinum
what is foodborne botulinum caused by?
The ingestion of a preformed
toxic neurotoxin grown by the organism in food.

illness is thus considered a food intoxication as opposed to an infection
C.botulinum E is carried by which animal?
Sea mammals
Which types are most common & of most concern to us?
Type A - western USA(meats & vegetables)

Type B - Europe (also found in eastern US)

Type E - Japan, Canada, US(associated with fish products)
what are the class of symptoms of C.botulinum?
1) GI symptoms

2) Neurological Symptoms
what are the GI symptoms?
nausea
vomiting
diarrhea
The neurological symptoms?
weakness
constipation
dizziness
genreal muscle weakness
vertigo
respiratory paralysis
facial weakness
pharyngolaryngeal paralysis
death
what is the Incubation period of Clostridium botulinum?
2 hours to 14 days
usually 12 - 36 hours.
NB. IP for Tpye E is shorter, the earlier the symptoms appear the more serious
what is the mode of action of the neurotoxin?
inhibition of ACH release
from motor neurons in muscles
secretory glands( salivary, sweat, tear)
what factors are most often contributing tooutbreaks of botulinum?
1)inadequate time / temperature during cooking

2)Inadequately processed foods
outbreaks of botulism in Canada & Japan are usually type E. Why?
usually associated with seafood
what 2 two test are often used in the lab as diagnosis for botulism?
1)mouse lethality

2)mouse neutralization
what is the Mouse lethality test?
determines whether or not we're dealing with botulism or something thats not botulisms. trying to determine whether or not the neurotoxin present is botulism
what is mouse neutralization test?
tells you which specific type of botulism occurs in meds. A,B,C